Results 31 to 40 of about 25,661 (263)

Zglobalizowana kultura medialna i jej superbohaterowie: serial-killer i terrorysta kamikadze. Patologia ofiarniczej wymiany

open access: yesEr(r)go, 2006
Wojciech Chyła, Superheroes of Globalised Media Culture: Serial Killer and Suicide Bomber. Pathology of Sacrificial Exchange The article analyses the discursive presence of a new type of pop-culture heroes, serial killer and suicide bomber, in the light ...
Wojciech Chyła
doaj  

Dr. Lecter y Mr. Dexter Morgan: mutaciones del héroe postclásico en la ficción televisiva

open access: yesÁrea Abierta, 2014
Este artículo pretende estudiar el héroe contemporáneo y sus transformaciones en la ficción serial televisiva, llevada en los últimos tiempos al extremo en la figura protagónica del serial killer en la ya finalizada Dexter (Showtime, 2006-2013) y en ...
Raquel Crisóstomo Gálvez
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

open access: yesMolecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen   +14 more
wiley   +1 more source

It happened to a friend of a friend: inaccurate source reporting in rumour diffusion

open access: yesEvolutionary Human Sciences, 2020
People often attribute rumours to an individual in a knowledgeable position two steps removed from them (a credible friend of a friend), such as ‘my friend's father, who's a cop, told me about a serial killer in town’. Little is known about the influence
Sacha Altay   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Denying the Darkness: Exploring the Discourses of Neutralization of Bundy, Gacy, and Dahmer

open access: yesSocieties, 2019
This exploratory study analyzed how three serial killers (i.e., Bundy, Gacy, and Dahmer) potentially rationalized and justified their murders by applying techniques of neutralization.
Veronyka James
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

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