Results 71 to 80 of about 556,751 (253)

Mediation today: The art of founding a mediation clinic [PDF]

open access: yes, 2021
A knowledge exchange paper entitled Mediation Today: The Art of Founding a Mediation Clinic, to raise awareness, provide guidance and assistance for those law schools proposing to set up and establish a mediation clinic. Presented on 6th February 2021 at
Waters, B.
core  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

How physical activity enhances academic engagement in middle school: a serial mediation model of interpersonal relationships and academic support

open access: yesFrontiers in Psychology
IntroductionAcademic engagement is a critical aspect of adolescent development. Understanding the mechanism of academic engagement will help to take effective measures to improve the academic engagement of middle school students. This study used a serial
Junmin Zhang   +3 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Fear of COVID-19 and Anxiety: Serial Mediation by Trust in the Government and Hope

open access: yes, 2023
Yong Yang, Huili Wang School of Educational Science, Xinyang Normal University, Xinyang, Henan, People’s Republic of ChinaCorrespondence: Yong Yang, School of Educational Science, Xinyang Normal University, Room 517, Xinyang, Henan, 464000, People’s ...
Yang Y, Wang H
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

AFRICAN-STYLE MEDIATION AND WESTERN-STYLE DIVORCE AND FAMILY MEDIATION: REFLECTIONS FOR THE SOUTH AFRICAN CONTEXT [PDF]

open access: yes, 2012
Both Western-styled mediation and African-styled mediation are practised in South Africa. Each of these models is applied in specific social contexts.
Boniface, AE, AE Boniface, Boniface, A E
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Peer mediation It's good to listen

open access: yes, 1997
SIGLEAvailable from British Library Document Supply Centre-DSC:q97/11666 / BLDSC - British Library Document Supply CentreGBUnited ...
Mediation UK, Bristol (United Kingdom)
core  

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