Results 81 to 90 of about 9,717,187 (276)

Serial order of maternal responses in mice

open access: yesAnimal Behaviour, 1969
Abstract One hundred and fifteen naive adult mice of both sexes were observed for 5 min with a 1- or 2-day-old pup. They all retrieved the pup, 113 of them licked the pup, seventy-five showed nest-building and eighty displayed the lactation-position. The order in which these responses were given seemed highly predictable.
openaire   +3 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

A Multi-disciplinary Approach to the Investigation of Aspects of Serial Order in Cognition [PDF]

open access: yes, 2002
Serial order processing or Sequence processing underlies many human activities such as speech, language, skill learning, planning, problem solving, etc.
Bapi, Raju S.   +2 more
core  

Resonant Suppression Method Based on PI control for Serial Manipulator Servo Drive System

open access: yesScience Progress, 2020
A typical serial manipulator consists of a servo motor, a serial mechanism and an independent joint placed between the motor and the serial mechanism.
Xiaopeng Li   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Serial control of phonology in speech production [PDF]

open access: yes
The aim of this thesis is to further our understanding of the processes which control the sequencing of phonemes as we speak: this is an example of what is commonly known as the serial order problem.
Vousden, Janet
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Animacy effects extend to working memory: results from serial order recall tasks

open access: yes, 2019
Words that represent animate entities (e.g., dog) are recalled from long-term memory more accurately than words representing inanimate entities (e.g., pan). In this research, we examined whether the animacy effect extends to working memory (WM).
Murphy, Karen   +2 more
core   +1 more source

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