Results 41 to 50 of about 711 (245)

Intraoperative Collection of Ascitic Fluid With Intra‐ or Postoperative Reinfusion in Ovarian Cancer: Safety and Feasibility of a Roller Pumping Method

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients with ovarian cancer often present with massive ascites, leading to significant protein loss during surgical procedures. Although cell‐free concentrated ascites reinfusion therapy (CART) is used in palliative settings to mitigate protein loss, its application in intraoperative settings remains unexplored.
Yutaka Yoneoka   +7 more
wiley   +1 more source

Norbert Moutier, Collection Aventures. L’enfance et la sérialité à l’œuvre

open access: yesComicalités, 2023
Norbert Moutier’s childhood graphic production compiles about 1000 original illustrated booklets, handmade from 1946 to 1960 by himself and his mother, Simonne Moutier. The whole is put in context by a series of 600 family photographs.
Xavier Girard
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

The role and implications of mammalian cellular circadian entrainment

open access: yesFEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Seriality at the Dawn of Photography: The Problem of Temporality [PDF]

open access: yesХудожественная культура
The 19th century became the first ‘Golden Age’ of seriality, having subordinated key spheres of public life to the principles of discreteness, decomposition, repetition, and variation: from the prolonged presentation of news and literary works (the ...
Smolev Daniil D.
doaj   +1 more source

Domesticating and Glocalising the Dreamy: McCay’s Little Nemo and Its Sequels in Early Italian Corriere dei Piccoli (1909-1914)

open access: yesInterfaces, 2021
The editors of Corriere dei Piccoli (CdP), an Italian comics magazine for children launched in December 1908, followed the New York Herald’s every step.
Eva Van de Wiele
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

'In This Corner of the World' and the Challenges of Intermedial Adaptation

open access: yesSeries. International journal of tv serial narratives, 2019
In This Corner of the World, a Japanese television drama broadcast in summer 2018, is an adaptation of Kōno Fumiyo’s critically acclaimed manga with the same title and also its feature-length anime version directed by Katabuchi Sunao.
Mitsuhiro Yoshimoto
doaj   +1 more source

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