Results 171 to 180 of about 7,591,914 (316)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Brechemin Piano Series April 7, 2016

open access: yes, 2016
Concert ProgramBrechemin Piano Series April 7 ...
Yeh, Kay Yen-Chun   +2 more
core  

Fentanyl purity and overdose decline: A reexamination of geographic trends. [PDF]

open access: yesSci Adv
Dasgupta N   +7 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Suspension bridge, Cincinnati

open access: yes
Steamboat passing under the Cincinnati-Covington Bridge, now the John A.

core  

Prospective estimation of water equivalent diameter and SSDE using 3D landmark CT scans. [PDF]

open access: yesJ Appl Clin Med Phys
Hernandez AM   +6 more
europepmc   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Summary of the 1980 Winter/Spring Film Series [PDF]

open access: yes
Summary of 1980 Winter/Spring film series for the Lifesize: Women and Film series (then called Films By and About Women) an initiative of the NSCAD Feminist Collective (then called the Women's Affairs Committee)
NSCAD Feminist Collective   +1 more
core  

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