Results 31 to 40 of about 8,251,979 (290)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen   +23 more
wiley   +1 more source

Joint Optimal Policy for Maintenance, Spare Unit Selection and Inventory Control Under a Partially Observable Markov Decision Process

open access: yesMathematics
This research investigates the joint optimization of maintenance and spare unit management for series systems composed of multiple heterogeneous units.
Nozomu Ogura, Mizuki Kasuya, Lu Jin
doaj   +1 more source

Sensor & instrumentation system : series 2 [PDF]

open access: yes, 2017
This book is an introduction to a number of the topics in sensor and instrumentation systems. Many of the topics describe the design experiments and system measurement especially in sensor applications.

core  

MYCN Amplification in RB1‐Inactivated Retinoblastoma: Association With High‐Risk Features

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background MYCN amplification occurs in a subset of retinoblastoma cases, both with and without RB1 inactivation. It has been suggested that retinoblastomas with MYCN amplification represent a distinct entity with more aggressive clinical behavior.
Kyriaki Papaioannou   +9 more
wiley   +1 more source

On predicting climate under climate change

open access: yesEnvironmental Research Letters, 2013
Can today’s global climate model ensembles characterize the 21st century climate in their own ‘model-worlds’? This question is at the heart of how we design and interpret climate model experiments for both science and policy support.
Joseph D Daron, David A Stainforth
doaj   +1 more source

Building Parsimonious Dynamic System for Time Series [PDF]

open access: yesالمجلة العراقية للعلوم الاحصائية, 2005
In this paper the radial basis function method is used for the generation of models of time series. It has been arrived at a model for nonlinear time series. It has also been found that the error is restricted between zero and one.
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

Computational Biochemistry: Systems Biology Minireview Series [PDF]

open access: yesJournal of Biological Chemistry, 2009
Understanding how biological processes work and are regulated requires that the biochemical mechanisms underlying the processes be described. The study of biochemical mechanisms permeates all of biological and biomedical sciences. A description of biochemical mechanisms requires multiple approaches. Over the past 50 years, many of these approaches have
openaire   +2 more sources

Estimation of System Parameters and Predicting the Flow Function from Time Series of Continuous Dynamical Systems

open access: yes, 2004
We introduce a simple method to estimate the system parameters in continuous dynamical systems from the time series. In this method, we construct a modified system by introducing some constants (controlling constants) into the given (original) system ...
Abarbanel   +20 more
core   +2 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

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