Results 81 to 90 of about 8,251,979 (290)

Elliptic hypergeometric series on root systems

open access: yesAdvances in Mathematics, 2004
We derive a number of summation and transformation formulas for elliptic hypergeometric series on the root systems A_n, C_n and D_n. In the special cases of classical and q-series, our approach leads to new elementary proofs of the corresponding identities.
openaire   +2 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Global System Change: A Whole System, Nature-Based Framework for Sustainability, System Change and Responsible Investing

open access: yesCadmus
Interest in system change is rising, driven largely by growing awareness that flawed economic and political systems are the root causes of climate change and other major challenges.
Frank Dixon
doaj  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

Using the Injection System as a Sensor to Analyze the State of the Electronic Automotive System

open access: yesSensors
This paper presents a novel diagnostic method that employs the fuel injection system as a sensor for monitoring internal combustion engine pressure, analysing series resistance to detect connector degradation, and evaluating needle movement within the ...
Matej Kucera   +4 more
doaj   +1 more source

Analysis of the Influence of Compensation Capacitance Errors of a Wireless Power Transfer System with SS Topology

open access: yesEnergies, 2017
In this study, in order to determine the reasonable accuracy of the compensation capacitances satisfying the requirements on the output characteristics for a wireless power transfer (WPT) system, taking the series-series (SS) compensation structure as an
Yi Wang   +3 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

An Improved Wireless Battery Charging System

open access: yesEnergies, 2018
This paper presents a direct wireless battery charging system. The output current of the series-series compensated wireless power transfer (SS-WPT) system is used as a current source, and the output voltage of AC-DC converter controls the current source.
Woo-Seok Lee   +3 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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