Results 51 to 60 of about 57,279 (308)

REVIEW OF CELIAC DISEASE PRESENTATION IN A PEDIATRIC TERTIARY CENTRE

Arquivos de Gastroenterologia
BACKGROUND: Celiac disease is an immune-mediated disorder with a multiform presentation and therefore a challenging diagnosis. OBJECTIVE: Our purpose is to identify the epidemiological, clinical, laboratory and histologic characteristics of children ...
Gracinda Nogueira OLIVEIRA, Rajiv MOHAN, Andrew FAGBEMI   +2 more
doaj   +1 more source

Diagnosis of patients with suspected chronic hepatitis C infection

Annals of Hepatology, 2010
The current optimal approach to detecting hepatitis C virus (HCV) infection involves screening people for risk factors and only testing selected individuals at risk.
Adrián Gadano, Omar Galdame, Sebastián Marciano   +2 more
doaj   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

Advanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang, Emilie Derisoud, Denise Parreira, Nayere Taebnia, Paulo R. Jannig, Reza Zandi Shafagh, Allan Zhao, Congru Li, Macarena Ortiz, Manuel Alejandro Maliqueo, Elisabet Stener‐Victorin, Volker M. Lauschke, Qiaolin Deng   +12 more
wiley   +1 more source

Comparación de técnicas para el serodiagnóstico de la leptospirosis humana Comparison of techniques for the serodiagnosis of human leptospirosis

Revista Cubana de Investigaciones Biomédicas, 2004
Se estudiaron 786 sueros pareados de pacientes con sospecha clínica, con evidencia epidemiológica de leptospirosis o sin esta, por las técnicas de hemaglutinación (HA) y microaglutinación (MAT), como técnica de referencia (gold standard), con el objetivo
Lelys Navarro Aguirre, Olga L González González, Ma. de Lourdes Sánchez Álvarez, Osmel Rodríguez García   +3 more
doaj  

A Lung‐Immune Dual‐Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses

Advanced Science, EarlyView.
Cryopreserved lung‐humanized mice overcome the dependency to fresh tissues and permit head‐to‐head profiling of all four human common cold coronaviruses versus SARS‐CoV‐2 infection; the model validates Paxlovid efficacy against HKU1 and, when coupled with human immune‐system engraftment, enables interrogation of lung‐resident human immunity and HKU1 ...
Chunyu Cheng, Jing Sun, Chun Lu, Qian Yu, Yiyun He, Bingqing Wu, Deshan Ren, Shuai Ding, Jincun Zhao, Yan Li   +9 more
wiley   +1 more source

Performance of serological tests PGL1 and NDO-LID in the diagnosis of leprosy in a reference Center in Brazil

BMC Infectious Diseases, 2019
Background Early detection of leprosy and multidrug therapy are crucial to achieve zero transmission and zero grade II incapacities goals of World Health Organization.
André Luiz Leturiondo, Ariani Batista Noronha, Monik Oney Oliveira do Nascimento, Cynthia de Oliveira Ferreira, Fabíola da Costa Rodrigues, Milton Ozório Moraes, Carolina Talhari   +6 more
doaj   +1 more source

Development and Head-to-Head Comparison of TwoColloidal gold Based SerologicLateral Flow Assays for SARS-CoV-2 Antibody Tests

Nano Biomedicine and Engineering, 2020
To combat the COVID-19 pandemic, serologic lateral flow immunoassays are required to facilitate accurate diagnosis of SARS-CoV-2 infection and confirmation of molecular results.
Jing Tian, Kan Wang, Yanlei Liu, Hui liang, Xueling Li, Daxiang Cui   +5 more
doaj   +1 more source

Palmitoylation‐Mediated Ubiquitination of SRPK1 Regulates Ferroptosis in High‐Fat‐Induced Erectile Dysfunction

Advanced Science, EarlyView.
Elevated exogenous palmitic acid promotes the S‐palmitoylation of SRPK1 in endothelial cells, a dynamic process governed by ZDHHC24 and APT1. This post‐translational modification strengthens the interaction between SRPK1 and the E3 ubiquitin ligase MIB1, thereby facilitating the proteasomal degradation of SRPK1.
Xiao‐Hui Tan, Ke‐Fan Li, Yi‐Ming Yuan, Man‐Cheng Xia, Fang‐Zhou Zhao, Hong‐Gang Ying, Zhuo Zhou, Peng‐Chao Gao, Guo‐Qing Xie, Xue‐Song Li, Hui Jiang, Rui‐Li Guan   +11 more
wiley   +1 more source

Multiplexed, quantitative serological profiling of COVID-19 from a drop of blood by a point-of-care test [PDF]

, 2020
Jacob T. Heggestad, David Kinnamon, Lyra B. Olson, Jason Liu, Garrett Kelly, Simone A. Wall, Cassio M. Fontes, Daniel Y. Joh, Angus Hucknall, Carl F. Pieper, Ibtehaj A. Naqvi, Lingye Chen, Loretta G. Que, Thomas H. Oguin, Smita K. Nair, Bruce A. Sullenger, Christopher W. Woods, Gregory D. Sempowski, Bryan Kraft, Ashutosh Chilkoti   +19 more
openalex   +1 more source

Alkaline Phosphatase‐Activated NIR‐II AIEgens Nanosystem for Surgical and Postoperative Closed‐Loop Therapy of Advanced Osteosarcoma

Advanced Science, EarlyView.
This study designed a tumor microenvironment‐responsive AIEgen nanoparticle for near‐infrared photoimmunotherapy, which inhibits primary tumors and metastasis by promoting pyroptosis and suppressing aerobic glycolysis. ABSTRACT In advanced osteosarcoma, tumor invasion often prevents complete resection, and immunotherapy is limited by the tumor's ...
Kaiyuan Liu, Ruotong Li, Li Zhang, Hengli Lu, Binhui Yang, Qian Hu, Yining Tao, Haoran Mu, Jing Han, Pengfei Zan, Jiakang Shen, Dongqing Zuo, Hongsheng Wang, Wei Sun, Xingjun Zhu   +14 more
wiley   +1 more source