Results 1 to 10 of about 1,302,007 (304)

SARS-CoV-2 multi-antigen serology assay [PDF]

Methods and Protocols, 2021
Serology tests are extremely useful for assessing whether a person has been infected with a pathogen. Since the onset of the COVID-19 pandemic, measurement of anti-SARS-CoV-2-specific antibodies has been considered an essential tool in identifying ...
Bourke, C, Mazhari, R, Hyslop, S, Williamson, DA, Kiernan-Walker, N, Robinson, LJ, Longley, RJ, Angrisano, F, Eriksson, EM, Chen, C, Ruybal-Pesántez, S, Mueller, I   +11 more
core   +3 more sources

Tensor‐structured decomposition improves systems serology analysis [PDF]

Molecular Systems Biology, 2021
Systems serology provides a broad view of humoral immunity by profiling both the antigen‐binding and Fc properties of antibodies. These studies contain structured biophysical profiling across disease‐relevant antigen targets, alongside additional ...
Zhixin Cyrillus Tan, Tan, Zhixin Cyrillus, Murphy, Madeleine C, Madeleine C Murphy, Hakan S Alpay, Meyer, Aaron S, Taylor, Scott D, Aaron S Meyer, Scott D Taylor, Alpay, Hakan S   +9 more
core   +2 more sources

Sensitivity and Specificity of Human Papillomavirus (HPV) 16 Early Antigen Serology for HPV-Driven Oropharyngeal Cancer: A Systematic Literature Review and Meta-Analysis

Cancers, 2021
Antibodies against HPV16 early proteins have been shown to be promising biomarkers for the identification of HPV-driven oropharyngeal cancer (HPV-OPC) among OPC cases in multiple studies.
Julia Hibbert, Tim Waterboer, Nicole Brenner, Gordana Halec, Dan Baaken   +4 more
core   +2 more sources

The novel Group A Streptococcus antigen SpnA combined with bead-based immunoassay technology improves streptococcal serology for the diagnosis of acute rheumatic fever

Journal of Infection, 2018
OBJECTIVES:Streptococcal serology provides evidence of prior Group A Streptococcus (GAS) exposure, crucial to the diagnosis of acute rheumatic fever (ARF) and post-streptococcal glomerulonephritis.
P. Rod Dunbar, Hanson-Manful, Paulina, Didsbury, Alicia, Paulina Hanson-Manful, Whitcombe, Alana, Nicole J. Moreland, Paul G. Young, Polly E. Atatoa Carr, Proft, Thomas, Alana L. Whitcombe, Bell, Anita, Mitchell, Edwin, Edwin A. Mitchell, Atatoa Carr, Polly E, Moreland, Nicole, Young, Paul, Dunbar, Peter, Thomas Proft, Alicia Didsbury, Anita Bell   +19 more
core   +2 more sources

Serology using rROP2 antigen in the diagnostic of toxoplasmosis in pregnant women

Revista do Instituto de Medicina Tropical de São Paulo, 2009
A toxoplasmose causa grave doença fetal durante a infecção aguda da gestante, assim demanda diagnóstico precoce para tratamento efetivo e preservação fetal. Os testes fetais são de baixa eficiência e o diagnóstico é baseado na sorologia para IgM materna,
Pires, Márcio, Andrade Jr., Heitor Franco de, Angel, Sérgio O., Macre, Miriam de Souza, Meireles, Luciana Regina   +4 more
core   +2 more sources

A Mathematical Analysis of Human Leukocyte Antigen Serology

, 1978
This paper presents and explores a comprehensive mathematical model for human leukocyte antigen serology, based on a mathematical formalization of the concept of specificity.
Bernard Amos, D., Woodbury, Max A., Markowsky, George, Nau, Dana S.   +3 more
core   +2 more sources

Evaluation of microscopy, serology, circulating anodic antigen (CAA), and eosinophil counts for the follow-up of migrants with chronic schistosomiasis: a prospective cohort study

Parasites & Vectors, 2021
Background An accurate test for the diagnosis and post-treatment follow-up of patients with schistosomiasis is needed. We assessed the performance of different laboratory parameters, including the up-converting reporter particle technology lateral flow ...
F. Tamarozzi, T. Ursini, Pytsje T. Hoekstra, Ronaldo Silva, Cecilia Costa, F. Gobbi, Gerardo B. Monteiro, L. Motta, G. V. van Dam, P. Corstjens, L. van Lieshout, D. Buonfrate   +11 more
semanticscholar   +1 more source

Systems serology-based comparison of antibody effector functions induced by adjuvanted vaccines to guide vaccine design

npj Vaccines, 2023
The mechanisms by which antibodies confer protection vary across vaccines, ranging from simple neutralization to functions requiring innate immune recruitment via Fc-dependent mechanisms.
C. Loos, M. Coccia, A. Didierlaurent, Ahmed Essaghir, J. Fallon, D. Lauffenburger, Corinne Luedemann, Ashlin R. Michell, R. G. van der Most, A. Zhu, G. Alter, W. Burny   +11 more
semanticscholar   +1 more source

Systems serology detects functionally distinct coronavirus antibody features in children and elderly

Nature Communications, 2021
The hallmarks of COVID-19 are higher pathogenicity and mortality in the elderly compared to children. Examining baseline SARS-CoV-2 cross-reactive immunological responses, induced by circulating human coronaviruses (hCoVs), is needed to understand such ...
K. Selva, C. E. van de Sandt, Melissa M. Lemke, Christina Y. Lee, Suzanne K. Shoffner, B. Chua, S. Davis, Thi H. O. Nguyen, L. Rowntree, Luca Hensen, M. Koutsakos, C. Y. Wong, F. Mordant, D. Jackson, K. Flanagan, Jane Crowe, S. Tosif, M. Neeland, P. Sutton, P. Licciardi, N. Crawford, Allen C. Cheng, D. Doolan, F. Amanat, F. Krammer, Keith J. Chappell, Naphak Modhiran, D. Watterson, P. Young, W. Lee, B. Wines, P. Mark Hogarth, R. Esterbauer, Hannah G. Kelly, Hyon-Xhi Tan, J. Juno, A. Wheatley, S. Kent, K. Arnold, K. Kedzierska, A. Chung   +40 more
semanticscholar   +1 more source

Serology Is More Sensitive Than Urea Breath Test or Stool Antigen for the Initial Diagnosis of Helicobacter pylori Gastritis When Compared With Histopathology.

American Journal of Clinical Pathology, 2020
OBJECTIVES To assess the concordance and performance characteristics of Helicobacter pylori laboratory tests compared with histopathology and to propose algorithms for the diagnosis of H pylori that minimize diagnostic error.
D. Bosch, Niklas Krumm, M. Wener, M. Yeh, C. Truong, D. Reddi, Yongjun Liu, P. Swanson, R. Schmidt, A. Bryan   +9 more
semanticscholar   +1 more source