Results 41 to 50 of about 274,252 (355)

JC virus-DNA detection is associated with CD8 fffector accumulation in peripheral blood of patients with multiple sclerosis under natalizumab treatment, independently from JC virus serostatus [PDF]

open access: yes, 2018
Although natalizumab (anti-α4 integrin) represents an effective therapy for relapsing remitting multiple sclerosis (RRMS), it is associated with an increased risk of developing progressive multifocal leukoencephalopathy (PML), caused by the polyomavirus ...
Anzivino, Elena   +16 more
core   +3 more sources

An In Vitro Microneutralization Assay for SARS‐CoV‐2 Serology and Drug Screening

open access: yesCurrent Protocols in Microbiology, 2020
The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) emerged in the city of Wuhan, Hubei Province, China, in late 2019. Since then, the virus has spread globally and caused a pandemic.
F. Amanat   +12 more
semanticscholar   +1 more source

Concentrations of Neopterin and Interleukin-10 in Peritoneal Fluid and in Serum of Women with Endometriosis

open access: yesPteridines, 2004
Endometriosis is a gynaecological disorder characterized by increased number and activation of peritoneal macrophages and release of macrophage-derived cytokines and growth factors. The aim of our work was t(5 study the level of neopterin and interleukin
Kondera-Anasz Zdzislawa   +4 more
doaj   +1 more source

The epidemiology of canine leishmaniasis: transmission rates estimated from a cohort study in Amazonian Brazil [PDF]

open access: yes, 1997
We estimate the incidence rate, serological conversion rate and basic case reproduction number (R0) of Leishmania infantum from a cohort study of 126 domestic dogs exposed to natural infection rates over 2 years on Marajó Island, Pará State, Brazil.
Courtenay, O.   +3 more
core   +1 more source

Serology for SARS-CoV-2: Apprehensions, opportunities, and the path forward

open access: yesScience immunology, 2020
Defining acceptable performance characteristics for SARS-CoV-2 serological tests requires factoring in how the results will be used. Serological testing for SARS-CoV-2 has enormous potential to contribute to COVID-19 pandemic response efforts.
Juliet E. Bryant   +13 more
semanticscholar   +1 more source

Evaluation of the Potential Diagnostic Utility of the Determination of Selected Caspases—Markers Involved in the Regulation of Apoptosis—In Patients with Ovarian Cancer

open access: yesDiagnostics, 2021
Ovarian cancer remains a major diagnostic and therapeutic problem in modern gynecological oncology. For this reason, research which focuses on the search for new diagnostic markers and the assessment of their possible usefulness in clinical practice is ...
Aleksandra Mielczarek-Palacz   +2 more
doaj   +1 more source

Liver involvement in pediatric celiac disease [PDF]

open access: yes, 2015
Celiac disease (CD) is an intestinal inflammatory disease that manifests in genetically susceptible individuals when exposed to dietary gluten. It is a common chronic disorder, with a prevalence of 1% in Europe and North America.
Anania, Caterina   +4 more
core   +1 more source

Optimizing high-yield production of SARS-CoV-2 soluble spike trimers for serology assays

open access: yesbioRxiv, 2020
The SARS-CoV-2 spike trimer is the primary antigen for several serology assays critical to determining the extent of SARS-CoV-2 exposure in the population.
D. Esposito   +12 more
semanticscholar   +1 more source

Challenges of Rabies Serology: Defining Context of Interpretation

open access: yesViruses, 2021
The case fatality rate of rabies, nearly 100%, is one of the most unique characteristic of this ancient virus infection. The crucial role rabies virus neutralizing antibody plays in protection is both well established and explanation of why rabies ...
S. Moore
semanticscholar   +1 more source

Changes in the Concentration of Markers Participating in the Regulation of the Apoptosis Receptor Pathway Involving Soluble Tumour Necrosis Factor Ligand inducing Apoptosis (sTRAIL) and Osteoprotegerin (OPG) in the Serum of Women with Ovarian Cancer—Participation in Pathogenesis or a Possible Clinical Use?

open access: yesCells, 2020
Due to the ability to selectively induce apoptosis in cancer cells, the most interesting target for clinical research is the tumour necrosis factor ligand inducing apoptosis (TRAIL), which binds specific receptors, including osteoprotegerin (OPG).
Aleksandra Mielczarek-Palacz   +2 more
doaj   +1 more source

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