Results 151 to 160 of about 349,425 (383)

Non-pneumococcal mitis-group streptococci confound detection of pneumococcal capsular serotype-specific loci in upper respiratory tract

PeerJ, 2013
We performed culture-based and PCR-based tests for pneumococcal identification and serotyping from carriage specimens collected in rural and urban Kenya.
M. G. Carvalho, F. Pimenta, Iaci Moura, Alexis Roundtree, R. Gertz, Zhongya Li, Geofrey Jagero, G. Bigogo, M. Junghae, L. Conklin, D. Feikin, R. Breiman, C. Whitney, B. Beall   +13 more
semanticscholar   +1 more source

Treating Hearing Loss: From Cochlear Implantation to Gene Therapy

Advanced Science, EarlyView.
Cochlear implantation is the primary treatment for deafness, restoring functional hearing in over a million people. Recently, gene therapy has enabled biological hearing restoration in a small number of patients with OTOF‐related mutations. This perspective evaluates both approaches, concluding that cochlear implants will remain the standard for most ...
Fan‐Gang Zeng, Jieyu Qi, Chen‐Chi Wu, Yilai Shu, Renjie Chai   +4 more
wiley   +1 more source

Machine Learning‐Assisted Infectious Disease Detection in Low‐Income Areas: Toward Rapid Triage of Dengue and Zika Virus Using Open‐Source Hardware

Advanced Intelligent Discovery, EarlyView.
This study introduces an affordable machine learning platform for simultaneous dengue and zika detection using fluorine‐doped tin oxide thin films modified with gold nanoparticles and DNA aptamers. Designed for low‐cost, hardware‐limited devices (< $25), the model achieves 95.3% accuracy and uses only 9.4 kB of RAM, demonstrating viability for resource‐
Marina Ribeiro Batistuti Sawazaki, Bassam Bachour Junior, Marcelo Mulato, José Ilton de Oliveira Filho   +3 more
wiley   +1 more source

Rabies screen reveals GPe control of cocaine-triggered plasticity. [PDF]

, 2017
Identification of neural circuit changes that contribute to behavioural plasticity has routinely been conducted on candidate circuits that were preselected on the basis of previous results.
AE Stepien, AH Gittis, B Weissbourd, BN Armbruster, Boris D. Heifets, C Hammond, C Lüscher, Christina K. Kim, CM Bäckman, D Lin, EJ Nestler, ES Boyden, F-M Zhou, G Schiavo, H Taniguchi, HH Yin, IR Wickersham, JA Shuen, JS Park, K Miyamichi, K Miyamichi, K Yonehara, Karl Deisseroth, Katherine E. DeLoach, Kevin T. Beier, KF Raab-Graham, KT Beier, L Madisen, L Petreanu, L Ye, LA Gunaydin, LA Schwarz, Lin Wai Hung, Liqun Luo, M Watabe-Uchida, M Xue, MJ Krashes, NR Wall, P Rajasethupathy, Paul Hoerbelt, PE Rothwell, PW Kalivas, RC Pierce, RL Albin, Robert C. Malenka, S Hippenmeyer, S Lammel, S Lammel, SHR Oliet, Sophie Neuner, Timothy J. Mosca, TJ Mosca, TJ Stachniak, TN Lerner, Y Smith   +54 more
core   +2 more sources

Construction of the First Russian Recombinant Live Attenuated Vaccine Strain and Evaluation of Its Protection Efficacy Against Two African Swine Fever Virus Heterologous Strains of Serotype 8

Vaccines
Background/Objectives: The spread of African swine fever virus (ASFV) has led to major economic losses to pork worldwide. In Russia, there are no developed or registered vaccines against ASFV genotype II, which is associated with numerous ASFV outbreaks ...
Andrey Koltsov, Mikhail Sukher, Sergey Krutko, Sergey Belov, Alexey Korotin, Sofia Rudakova, Sergey Morgunov, Galina Koltsova   +7 more
doaj   +1 more source

Qualitative and Quantitative Analysis of Salmonella spp. in Broilers Technological Processing and Determination of a Performance Objective (PO) for Frozen Chicken Breast [PDF]

Brazilian Journal of Poultry Science
The present study investigated the frequency, level of contamination and serotyping of Salmonella strains isolated from broiler flocks in different processing sites and the fulfillment of a Performance Objective (PO) in frozen chicken breasts, as a risk ...
SCA Machado, VLA Pereira, MHC Aquino, A Giombeli, DP Rodrigues, ER Nascimento   +5 more
doaj   +2 more sources

AI‐Driven Microphysiological Systems for Advancing Nanoparticle Therapeutics

Advanced Intelligent Systems, EarlyView.
This review outlines recent advances in integrating artificial intelligence with microphysiological systems for nanoparticle evaluation. It highlights data‐driven optimization, image‐based prediction, and AI‐enabled analysis frameworks that advance translational research and support the development of personalized nanomedicine. Nanoparticles (NPs) play
Yedam Lee, Jaehong Min, Sujin Kim, Jihoon Ko   +3 more
wiley   +1 more source

Dengue Virus Serotype 3 Origins and Genetic Dynamics, Jamaica

Emerging Infectious Diseases
We identified 3 clades of dengue virus serotype 3 belonging to genotype III isolated during 2019–2020 in Jamaica by using whole-genome sequencing and phylogenomic and phylogeographic analyses. The viruses likely originated from Asia in 2014.
Shanice A. Redman, Lester J. Perez, Kenn Forberg, Keisha Francis, Jerome P. Walker, Tamara K. Thompson, Heather Phillips, Gavin A. Cloherty, Michael G. Berg, Joshua J. Anzinger   +9 more
doaj   +1 more source

ESCHERICHIA COLI O111a, 111c:B4. A NEW SEROTYPE ISOLATED FROM MONKEYS [PDF]

, 1955
W. H. Ewing, Mildred M. Galton, Kaitlyn Tanner   +2 more
openalex   +1 more source

Molecular dynamics of the host response to Streptococcus pneumoniae pneumonia in baboons

Animal Models and Experimental Medicine, EarlyView.
Using an established, clinically relevant nonhuman primate model of S. pneumoniae pneumonia, this study aims to identify novel potential molecular diagnostic and therapeutic targets using peripheral blood bulk transcriptomic, unbiased proteomic, and cytokine measurements. The constructed models were highly accurate in classifying bacterial pneumonia in
Bryan D. Kraft, Ashlee M. Valente, Ephraim L. Tsalik, Micah T. McClain, Marshall Nichols, Thomas W. Burke, Ricardo Henao, Erik J. Soderblom, J. Will Thompson, M. Arthur Moseley, Lori L. Hudson, Timothy Veldman, Olga M. Better, Mert Aydin, Anna Mazur, Karen E. Welty‐Wolf, Claude A. Piantadosi, Geoffrey S. Ginsburg, Christopher W. Woods   +18 more
wiley   +1 more source