Results 181 to 190 of about 241,652 (335)

Side effects of pesticides used in organic and conventional tomato crops on Dolichogenidea gelechiidivoris, a parasitoid of Tuta absoluta

open access: yesPest Management Science, EarlyView.
This study reveals strong variability in the effects of eight tomato integrated pest management‐compatible pesticides on Dolichogenidea gelechiidivoris, identifying harmful compounds such as spinosad and more selective ones such as sulfur and spiromesifen, depending on the exposure route.
Pablo Urbaneja‐Bernat   +3 more
wiley   +1 more source

Update on Gene Therapy in the Treatment of Hereditary Hearing Loss

open access: yesSensory Neuroscience, EarlyView.
Gene therapy is a promising therapeutic approach for genetic disorders, including three major gene therapy strategies: gene replacement, gene suppression, and gene editing. After transmitting genes to the inner ear through appropriate pathways, repair the cochlea in order to achieve the goal of treating hereditary hearing loss.
Weiwei He   +7 more
wiley   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

open access: yesSmall, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa   +4 more
wiley   +1 more source

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

open access: yesSmall, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti   +5 more
wiley   +1 more source

3D Quantification of Viral Transduction Efficiency in Living Human Retinal Organoids

open access: yesSmall Methods, EarlyView.
Optimization of viral vectors and their testing in human tissue is crucial to gene therapy development. Conventional technologies to assess virus transduction either lack spatial or temporal information. Here, spatiotemporal mapping of virus transduction in living retinal tissue is introduced, levering fluorescence imaging and machine learning‐based ...
Teresa S. Rogler   +11 more
wiley   +1 more source

Salmonellosis in lambing ewes with associated human infection

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract Salmonellosis in sheep is an infrequent diagnosis, but outbreaks do occur with abortion, diarrhoea and death possible sequelae. In this case, affecting a flock of 4000 ewes, Salmonella typhimurium definitive phage type 104 was isolated from clinical cases and a variety of environmental samples taken from the farm.
Joseph W. Angell   +2 more
wiley   +1 more source

Treatment of Neurogenic Voice Disorders

open access: yesWorld Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT This overview serves as a foundational resource for clinicians caring for neurologically complex patients presenting with voice complaints. Neurogenic voice disorders are diverse in their clinical presentations and therapeutic approaches. A thorough medical history, including family history, detailed laryngeal examination, voice assessments ...
Mausumi Syamal
wiley   +1 more source

Home - About - Disclaimer - Privacy