Results 211 to 220 of about 237,727 (286)

Development of Dose‐Response Models for the Ingestion Exposure Route and Stillbirth Outcome for Listeria monocytogenes

Risk Analysis, Volume 46, Issue 4, April 2026.
ABSTRACT Foodborne listeriosis can cause stillbirth in pregnant individuals, prompting numerous population‐specific food safety guidelines. Dose‐response models are employed in quantitative microbial risk assessments (QMRAs) to develop such guidelines; however, pregnant hosts are under‐considered when developing dose‐response models, and the few ...
Tyler Stump, Carly Gomez, Jade Mitchell
wiley   +1 more source

Assessing the diagnostic performance of clinical, serological and molecular approaches to improve dengue case detection in the Peruvian Amazon. [PDF]

PLoS Negl Trop Dis
Hauner A, Aroni-Sierra J, Merino X, Villa C, Torres F, Lagatie O, Talledo M, Ariën KK, Falconi-Agapito F.   +8 more
europepmc   +1 more source

Using Risk–Benefit Analysis and the Analytical Hierarchy Process to Decide on the Implementation of Rapid Salmonella Detection Methods in Large Poultry Industries

Risk Analysis, Volume 46, Issue 4, April 2026.
ABSTRACT Tools based on multi‐criteria decision analysis (MCDA) can be used in decision‐making processes related to food safety issues (FSI). We used risk–benefit analysis (RBA) and the analytic hierarchy process (AHP) to answer the following questions: What are the benefits and risks of using rapid Salmonella assays in large‐scale poultry industries ...
Cris Rocha Pinto Magalhães, Nathanyelle Soraya Martins de Aquino, Eduardo Cesar Tondo   +2 more
wiley   +1 more source

CBP/β‐Catenin Signaling in Hepatocytes Plays Pivotal Roles in MMP‐7‐Mediated Liver Fibrosis in a Metabolic Dysfunction‐Associated Steatohepatitis Mouse Model

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
CDAHFD‐induced hepatic steatosis stimulates CBP/β‐catenin signaling in hepatocytes, leading to increased production of the downstream effector MMP‐7. Hepatocyte‐derived MMP‐7 contributes to fibrogenic responses and is associated with the progression of liver fibrosis.
Jun Imamura, Masamichi Kimura, Yumi Otoyama, Koji Nishikawa, Michinori Kohara, Kiminori Kimura   +5 more
wiley   +1 more source

Challenges and Opportunities in the Development of Dengue Vaccines: A Comprehensive Review. [PDF]

Adv Biomed Res
Moghadasi R, Yadollahi Fars Y, Nasri H, Momenzadeh M.   +3 more
europepmc   +1 more source

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel, Manuel J. Verganista, Nuno R. Candeias   +2 more
wiley   +1 more source

Advancing the Landscape of RNAi Nanotherapeutics for Ischemic Heart Disease

Advanced Materials, Volume 38, Issue 17, 20 March 2026.
RNA interference (RNAi) nanomedicine revolutionizes treatment regimens for ischemic heart diseases by enabling tailored, sequence‐anchored gene regulation. This review highlights the recent advances in nanotechnology‐driven RNAi therapeutics for myocardial ischemia and discusses the key design principles that govern efficient delivery, providing ...
Han Gao, Da Pan, Hélder A. Santos
wiley   +1 more source

An overview of the clinical development of the 20-valent pneumococcal conjugate vaccine in adults. [PDF]

Hum Vaccin Immunother
McElwee K, Vojicic J, Sabharwal C, Ginis J, Peng Y, Mircus G, Watson W, Anderson A.   +7 more
europepmc   +1 more source

Label‐Free Detection of PSA Using Laser‐Induced Graphene/ZnO Nanorod‐Based Impedimetric Immunosensors

Advanced Sensor Research, Volume 5, Issue 3, March 2026.
A label‐free impedimetric immunosensor based on laser‐induced graphene decorated with ZnO nanorods is developed for prostate‐specific antigen detection. Antibody adsorption on ZnO enables clinically relevant sensitivity and an unconventional “signaling‐off” response, where charge‐transfer resistance decreases upon antigen binding, challenging ...
Maria S. Soares, Sónia O. Pereira, António J. S. Fernandes, Florinda M. Costa, Nuno F. Santos   +4 more
wiley   +1 more source