Results 291 to 300 of about 265,799 (334)

Nonalcoholic Fatty Liver Disease Exacerbates the Advancement of Renal Fibrosis by Modulating Renal CCR2+PIRB+ Macrophages Through the ANGPTL8/PIRB/ALOX5AP Axis

Advanced Science, Volume 12, Issue 46, December 11, 2025.
The ANGPTL8/PIRB/ALOX5AP axis mediates liver‐kidney crosstalk. Hepatocytes secrete ANGPTL8, which binds to CCR2+PIRB+ macrophages in the kidneys, affecting the expression of ALOX5AP and enhancing the activation of these macrophages. Activated cells produce TGF‐β, IL‐6, and IL‐23, driving Th17 activation and promote the formation of myofibroblasts ...
Shuqi Wei, Diwen Shou, Siyuan Huang, Yingsi Wang, Quanzhen Liu, Jinfa Liu, Xiaoyu Lv, Yuyi Zeng, Liting Wei, Han Lin, Jiechuan Chen, Yangxiao Chen, Haoyu Zhong, Yanqing Zhou, Wen Ma, Li Wang, Guojun Qian, Jing Guo, Donglin Sun   +18 more
wiley   +1 more source

Serotype 3 pneumococcal pleural empyema: a case report and review of the epidemiology. [PDF]

Eur Clin Respir J
Thoustrup Legardt Johansen M, Kristensen Lomholt F, Jensen JS, Harboe ZB.   +3 more
europepmc   +1 more source

AI‐Driven Microphysiological Systems for Advancing Nanoparticle Therapeutics

Advanced Intelligent Systems, Volume 7, Issue 12, December 2025.
This review outlines recent advances in integrating artificial intelligence with microphysiological systems for nanoparticle evaluation. It highlights data‐driven optimization, image‐based prediction, and AI‐enabled analysis frameworks that advance translational research and support the development of personalized nanomedicine. Nanoparticles (NPs) play
Yedam Lee, Jaehong Min, Sujin Kim, Jihoon Ko   +3 more
wiley   +1 more source

Elucidation of the binding interaction interface between AAV serotype 11 capsid protein and host nuclear import proteins

Mikayla Hoad, Sepehr Nematollahzadeh, Justin A Roby, Gualtiero Alvisi, Jade K. Forwood   +4 more
openalex   +1 more source

Antimicrobial activity of β-lactam antibiotics against pneumococcal isolates causing pneumococcal disease in adults immediately before and after the COVID-19 pandemic in Spain (2019-2020). [PDF]

Front Pharmacol
Llamosí M, Pérez-García C, Úbeda A, Vidal-Alcántara EJ, Pareja-Cerbán I, Gómez-Rubio E, Coronel P, Sanz JC, Domenech M, Sempere J, Yuste J.   +10 more
europepmc   +1 more source

Zebrafish: A Versatile and Powerful Model for Biomedical Research

BioEssays, Volume 47, Issue 12, December 2025.
Zebrafish are vital for advancing precision medicine, offering a genetically tractable and optically transparent vertebrate model with strong genetic homology to humans. They enable rapid and cost‐effective disease modeling and drug discovery, accelerating insights into cardiovascular, neurological, metabolic, and oncological disorders through gene ...
Sundus Siddiqui, Hiba Siddiqui, Emna Riguene, Michail Nomikos   +3 more
wiley   +1 more source

Transcriptomic analysis of <i>Streptococcus pneumoniae</i> serotype 1 reveals serotype-specific gene regulation. [PDF]

Microb Genom
Pongchaikul P, Hokamp K, Kjos M, Chaguza C, Audshasai T, Panagiotou S, Yahya R, Bricio-Moreno L, Hinton JCD, Kadioglu A, O'Brien M.   +10 more
europepmc   +1 more source

M/G‐Ratio‐Tuned Calcium Alginate Hydrogel Microcarrier for Controlled Delivery of Adeno‐Associated Virus for Gene Therapy

Biotechnology and Bioengineering, Volume 122, Issue 12, Page 3433-3445, December 2025.
ABSTRACT This paper proposes the controlled release of adeno‐associated virus (AAV) by polymer mesh structures of alginate hydrogel microbeads (gel‐beads). The polymer mesh structure of alginate hydrogel can be controlled by adjusting the number of cross‐linking points depending on the molecular structure (M/G ratio) of the alginate hydrogel.
Aiki Hioki, Shuhei Takatsuka, Yuta Kurashina, Hiroaki Onoe   +3 more
wiley   +1 more source

Genetic diversity of Streptococcus suis serotypes 2 and 1/2 isolates recovered from carrier pigs in closed herds.

, 2002
Gabriela Martínez, Josée Harel, Sonia Lacouture, Marcelo Gottschalk   +3 more
openalex   +1 more source