Experimental Infection with Mycobacterium Avium, Serotype 2, in Pigs
, 1977 J. Berg Jørgensen
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Advanced Science, Volume 12, Issue 15, April 17, 2025.Wenxiang Meng and colleagues delve into the molecular mechanisms underlying curcumin's modulation of RNA post‐transcriptional N (6)‐methyladenosine (m6A) modification. It is found that curcumin interacts with the Z1‐type protein tyrosine phosphatase receptor (PTPRZ1), maintaining its enzymatic activity and thus regulating the phosphorylation of the m6A‐
Ninan Zhang +9 more
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Streptococcus pneumoniae serotype distribution in low- and middle-income countries of South Asia: Do we need to revisit the pneumococcal vaccine strategy? [PDF]
Hum Vaccin ImmunotherDhawale P +8 more
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Chchd10: A Novel Metabolic Sensor Modulating Adipose Tissue Homeostasis
Advanced Science, Volume 12, Issue 15, April 17, 2025.Chchd10 is a novel regulator of adipose tissue (AT) homeostasis upon excess energy intake. Rapid Chchd10 reduction in response to high‐fat diet induction promotes adipogenesis in subcutaneous AT to store excess energy. On the other hand, sustained Chchd10 reduction protects visceral AT from 4‐HNE‐induced adipocyte dysfunction, attenuating the ...
Xiaoping Wu +11 more
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Genomic Diversity, Virulome, and Resistome of <i>Streptococcus agalactiae</i> in Northeastern Brazil: Are Multi-Host Adapted Strains Rising? [PDF]
PathogensPerez VP +9 more
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Brain‐Wide Neuroregenerative Gene Therapy Improves Cognition in a Mouse Model of Alzheimer's Disease
Advanced Science, Volume 12, Issue 14, April 10, 2025.NeuroD1 mediates brain‐wide astrocyte‐to‐neuron gene therapy conversion in 5xFAD mouse brain. Regenerated neurons can fire action potentials and integrate into pre‐existing neural networks, ultimately improving cognition in AD mice. Abstract Alzheimer's disease (AD) is a progressive and irreversible brain disorder with extensive neuronal loss in the ...
Zheng Wu +10 more
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Advanced Science, Volume 12, Issue 13, April 3, 2025.Lumbar instability mediates cartilage endplate degeneration with YAP translocation and stability. Here, it is determined that circSMAD4, a Yap1‐related circRNA, is shown to combine and regulate Yap1 mRNA through the formation of the ternary complexes with the m6A reader IGF2BP1.
Hanwen Li +10 more
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Urticaria-Like Hypersensitivity Reaction Following Botulinum Toxin Injection: A Case Report of Possible Interaction with β-Lactam Antibiotics. [PDF]
Int Med Case Rep JFeng W, Liu H.
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TRIM56 Promotes White Adipose Tissue Browning to Attenuate Obesity by Degrading TLE3
Advanced Science, Volume 12, Issue 13, April 3, 2025.This study pinpoints TRIM56 as a viable candidate for promoting white adipose tissue browning and as a promising therapeutic target for addressing obesity and metabolic disorders. Functioning as an E3 ubiquitin ligase, TRIM56 facilitates the degradation of the TLE3 protein, thereby accelerating the thermogenic process and enhancing energy expenditure ...
Haojie Qin +5 more
wiley +1 more source
Genetic characterization of foot-and-mouth disease virus in cattle in Northern Egypt. [PDF]
Vet WorldYousef SG +5 more
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