Vaccination and transfusion safety at the time of expanding use of live attenuated vaccines
Vox Sanguinis, EarlyView.
Pierre Tiberghien +4 more
wiley +1 more source
Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng +2 more
wiley +1 more source
Towards decentralization of <i>Salmonella</i> serotyping and risk assessment in poultry production environments with nanopore sequencing. [PDF]
Karunarathna R +5 more
europepmc +1 more source
Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu +15 more
wiley +1 more source
A two-year study of <i>Salmonella</i> in four natural watersheds highlights the need for increased environmental <i>Salmonella</i> surveillance to close the One Health loop. [PDF]
Smith JC +4 more
europepmc +1 more source
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng +8 more
wiley +1 more source
Identification of a new Salmonella serovar - Salmonella Weitmar (8:z41:1,5). [PDF]
Téllez-Castillo CJ +4 more
europepmc +1 more source
The essential oil and major compounds from Piper cyrtopodon exhibit potent, long‐lasting repellent activity against Aedes aegypti mosquitoes, combined with low cytotoxicity and favorable molecular docking interactions with odorant‐binding proteins. These findings highlight its potential for the development of alternative products for bite prevention ...
Maria L. L. da Costa +7 more
wiley +1 more source
Integrated matrix-assisted laser desorption ionization time-of-flight mass spectrometry serotype-specific peak analysis and <i>trans</i>-cinnamic acid antimicrobial activity against <i>Salmonella</i> spp. from the poultry chain. [PDF]
Jirapanth N +6 more
europepmc +1 more source
Spinal muscular atrophy (SMA) is a severe neuromuscular disease with emerging therapeutic complexity. This review aims to systematically map the global pipeline of investigational treatments for SMA. Using ClinicalTrials.gov and complementary international registries, we identified 21 planned or ongoing interventional trials from 2020 to 2025 targeting
Andrej Belančić +7 more
wiley +1 more source

