Results 51 to 60 of about 14,156 (243)

Serous retinal detachment after trabeculectomy in angle recession glaucoma

GMS Ophthalmology Cases, 2015
An 18-year-old male with 360 degree angle recession after blunt trauma in his right eye developed uncontrolled intraocular pressure (IOP) despite four antiglaucoma medications (AGM) with advancing disc damage.
Roy, Avik Kumar, Padhy, Debananda
doaj   +1 more source

Multidimensional en-face OCT imaging of the retina. [PDF]

, 2009
Fast T-scanning (transverse scanning, en-face) was used to build B-scan or C-scan optical coherence tomography (OCT) images of the retina. Several unique signature patterns of en-face (coronal) are reviewed in conjunction with associated confocal images ...
Adrian G. Podoleanu, Cucu, de Boer, George M. Dobre, Gh, Gh, Gh, Gh, Gh, Gh, Gh, Gh, Hitzenberger, Hong, Huber, Jiao, John Rogers, Justin Pedro, Leitgeb, Lim, Mark Hathaway, Masters, Merino, Patricia Garcia, Philippe Laissue, Pircher, Pircher, Pircher, Pircher, Richard B. Rosen, Rosa, Tuohy, Van Velthoven, Wojtkowski, Yasuno   +34 more
core   +1 more source

Cis‐ and Trans‐Regulatory Factors Independently Shape Phenotypic Heterogeneity of Retinitis Pigmentosa

Advanced Science, EarlyView.
A zebrafish model carrying an identical human RHO S334X allele reveals two independent genetic layers shaping retinitis pigmentosa (RP) severity: a protective 3‐bp cis‐regulatory insertion that attenuates transgene expression, and a dominant trans‐acting modifier that restores a severe phenotype.
Cong Cui, Kotone Nakagawa, Takumi Tateno, Ayaka Dan, Dexin Meng, Yoshihiro Omori, Soma Tomihara, Suzuri Okamoto, Shigeru Sato, Motokazu Tsujikawa   +9 more
wiley   +1 more source

Serous retinal detachment in preeclampsia and malignant hypertension [PDF]

Eye, 2019
To compare and evaluate the characteristics of hypertensive choroidopathy with serous retinal detachment in preeclampsia and malignant hypertension (HTN) and explore choroidal ischemia as a pathogenesis using multimodal imaging.A retrospective multicenter case series. Medical charts were reviewed.
Christopher Seungkyu Lee, Eun Young Choi, Minsub Lee, Heesuk Kim, Hyewon Chung   +4 more
openaire   +3 more sources

Fhod3 in zebrafish supports myofibril stability during growth of embryonic skeletal muscle

Developmental Dynamics, EarlyView.
Abstract Background Actin filament organization in cardiomyocytes critically depends on the formin Fhod3, but a role for Fhod3 in skeletal muscle development has not yet been described. Results We demonstrate here that in zebrafish mutated for one of two fhod3 paralog genes, fhod3a, skeletal muscle of the trunk appears normal through 2 days post ...
Aubrie Russell, Tracy Eng, Jeffrey D. Amack, David Pruyne   +3 more
wiley   +1 more source

PACHYCHOROID: an inherited condition? [PDF]

, 2015
PURPOSE: Thick choroid (pachychoroid) is associated with central serous chorioretinopathy (CSC), but whether pachychoroid is inherited is unknown. METHODS: In a prospective observational study, first- or second-degree relatives (16 individuals) of 5 ...
Behar-Cohen, F., Beydoun, T., Bousquet, E., Lehmann, M.   +3 more
core   +1 more source

Berberine alleviates cell pyroptosis in diabetic retinopathy by regulating AKT1, JUN, and STAT3

Ibrain, EarlyView.
Berberine alleviates diabetic retinopathy by reducing pyroptosis through AKT1/JUN/STAT3 regulation, as validated in rat models via network pharmacology, molecular docking, and experimental assays. Abstract Berberine (BBR) exerts an effective protection for diabetic retinopathy (DR), but the underlying key molecular mechanism remains unknown; this study
Na Li, Ji‐Lin Chen, Yi‐Jian Sun, Jia‐Fan Sun, Fatin Athirah Pauzi, Song‐Lin Zhu, Amy Yi Hsan Saik, Alan Han‐Kiat Ong   +7 more
wiley   +1 more source

Prepapillary Vascular Loops Complicated by Suspected Macroaneurysm Rupture

Case Reports in Ophthalmological Medicine, 2014
We present a case of prepapillary vascular loops complicated by a suspected macroaneurysm rupture which was treated with intravitreal bevacizumab (IVB). A 62-year-old woman presented with decreased vision and myodesopsia in her left eye.
Kei Akaiwa, Yoshinori Mitamura, Takashi Katome, Kentaro Semba, Mariko Egawa, Takeshi Naito   +5 more
doaj   +1 more source

Choroidal mast cells in retinal pathology: a potential target for intervention. [PDF]

, 2015
Mast cells are important in the initiation of ocular inflammation, but the consequences of mast cell degranulation on ocular pathology remain uncharacterized.
Behar-Cohen, F., Bergin, C., Besson-Lescure, B., Bousquet, E., Castaneda, B., de Kozak, Y., Lorena, V., Naud, M.C., Thillaye-Goldenberg, B., Zhao, M.   +9 more
core   +1 more source

METTL14 Ameliorates Mitochondrial Dysfunction and Autophagy in Lens Epithelial Cells of Diabetic Cataracts via m6A Modification of RPL3

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Diabetic cataracts are a leading cause of blindness, with lens epithelial cells (LECs) exhibiting mitochondrial dysfunction and autophagy inhibition under high glucose (HG) conditions. Methyltransferase‐like 14 (METTL14), an RNA methyltransferase, regulates N6‐methyladenosine (m6A) RNA modification; however, its role in modulating ...
Rui Li, Xue Wang, Wei Du, Qian Li, Hong‐Ping Cui   +4 more
wiley   +1 more source