Results 181 to 190 of about 3,353 (218)

Avian diversity and ethnoornithology in Pawukon - a 19th-Century Javanese manuscript : informing contemporary conservation of vulnerable species. [PDF]

J Ethnobiol Ethnomed
Putri RA, Ekowati VI, Dwiadmojo GN.
europepmc   +1 more source

Faces and phases of epistemic curiosity in science learning: A longitudinal study

British Journal of Developmental Psychology, EarlyView.
Different faces of epistemic curiosity shape science learning across development. While early scientific reasoning depends on the joint action of interest‐type and deprivation‐type curiosity, science knowledge is robustly driven by interest‐type curiosity, revealing a developmental reweighting of motivational mechanisms.
Susanne Koerber, Christopher Osterhaus
wiley   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

Parkinsonism Associated with Snakebite.

Ann Afr Med
Verma R, Prabhu V, Bal KPA.
europepmc   +1 more source

Cancer pain: current practice and emerging targets

British Journal of Pharmacology, EarlyView.
Cancer pain (CP) arises from a complex interplay between the tumour and its microenvironment. Many patients experience a mixed pain phenotype that encompasses nociceptive, neuropathic and neuroinflammatory mechanisms, and vary across tumour type and disease stage. Despite decades of intensive research, the mainstay of cancer pain treatment is still non‐
Yi Ye, Marcin Chwistek, Zhiting Gong, Vanessa Uzonwanne, Xiaojie Shi, Arpad Szallasi   +5 more
wiley   +1 more source

The selective degradation of PDE4B shortform, using a PROTAC, leads to inhibition of several hallmarks of cancer in HCT116 cells

British Journal of Pharmacology, EarlyView.
Background and Purpose Colorectal cancer is one of the most prevalent cancers worldwide, and novel precision medicine approaches are rapidly improving patient outcomes. Phosphodiesterase 4B (PDE4B) is a member of an enzyme family (PDE4) that hydrolyses intracellular cAMP to control spatial and temporal signalling cues.
Alina Zorn, John Daniel Pediani, Madihah Hussain, Jiayue Ling, Elaine Brown, Igor Belka, Eduardo Torres, Cathy Swindlehurst, Kyle Chan, David Stirling, George S. Baillie, Yuan Yan Sin   +11 more
wiley   +1 more source

Basis Networks: Learning basis functions for free‐form triangulations

Computer Graphics Forum, EarlyView.
Abstract We present a framework for learning compactly supported basis functions that define tangent continuous surfaces based on coarse irregular triangle meshes. The basis functions are represented as MLPs. Smoothness of the basis functions is achieved by using the values of Loop basis functions as the parameterization of the surface.
T. Djuren, M. Alexa
wiley   +1 more source

Molecular characterization and expression analysis of GATA1 in the blood clam Anadara granosa reveals its role in gonadal development. [PDF]

BMC Genomics
Xu Y, Zhang C, Zhang L, Wang J, Liu H, Bao Y.   +5 more
europepmc   +1 more source

Exploring children's experiences of schooling in Tanzania: How the ‘hidden curriculum’ undermines aspirations for sustainable development

Children &Society, EarlyView.
Abstract In the context of aspirations that firmly position education as the key to multiple global development goals, we raise concerns about how education is experienced by many children, particularly in low‐income, postcolonial contexts. Drawing from two, in‐depth qualitative studies in Tanzania, we demonstrate that existing pedagogical practices ...
Laela Adamson, Rhona Brown
wiley   +1 more source

Microchimerism and the need to rethink sex and gender binaries. [PDF]

Biol Sex Differ
Shildrick M.
europepmc   +1 more source