Results 11 to 20 of about 32,045 (241)

A "glympse" into neurodegeneration: Diffusion MRI and cerebrospinal fluid aquaporin-4 for the assessment of glymphatic system in Alzheimer's disease and other dementias. [PDF]

Hum Brain Mapp
MRI glymphatic biomarkers were analyzed in 111 prospectively recruited subjects with suspected dementia. Forty nine out of 111 subjects also underwent quantification of CSF‐AQP4. Neurodegeneration is associated with diffuse changes of glymphatic biomarkers and AQP4 levels in the CSF, which are partly dependent on disease stage and measures of ...
Sacchi L, D'Agata F, Campisi C, Arcaro M, Carandini T, Örzsik B, Dal Maschio VP, Fenoglio C, Pietroboni AM, Ghezzi L, Serpente M, Pintus M, Conte G, Triulzi F, Lopiano L, Galimberti D, Cercignani M, Bozzali M, Arighi A.   +18 more
europepmc   +2 more sources

Neuron-Derived Extracellular Vesicles: Emerging Biomarkers and Functional Mediators in Alzheimer's Disease, With Comparative Insights Into Neurodevelopment and Aging. [PDF]

Dev Neurobiol
ABSTRACT Alzheimer's disease (AD) is one of the most common neurodegenerative disorders characterized by the accumulation of amyloid‐β (Aβ) peptide and phosphorylated tau protein in the brain. Despite intensive efforts, early diagnosis and monitoring of AD remain challenging due to the lack of reliable biomarkers that can detect the disease in its ...
Gonul CP, Karacicek B, Genc S.
europepmc   +2 more sources

Cross-country variance in facial emotion recognition in presymptomatic and symptomatic behavioral variant frontotemporal dementia: Insights from the GENFI and ReDLat consortia. [PDF]

Alzheimers Dement
Abstract INTRODUCTION We investigated international differences in facial emotion recognition (FER) across stages of frontotemporal dementia (FTD). Previous studies may have missed early decline by combining data and masking variations in FER across countries.
de Boer L, Jiskoot LC, Seelaar H, van Swieten JC, Ibanez A, Maito M, Fittipaldi S, De Houwer JFH, Swartenbroekx T, Boesjes PA, Convery RS, Ferry-Bolder E, Foster P, Bouzigues A, Chisman-Russell L, van den Berg E, Papma J, Franzen S, Bourdage R, Rowe JB, Borroni B, Galimberti D, Tiraboschi P, Masellis M, Finger E, Laforce R, Graff C, Gerhard A, Sanchez-Valle R, Mendonça A, Moreno F, Synofzik M, Vandenberghe R, Ducharme S, Le Ber I, Levin J, Lebouvier T, Nacmias B, Otto M, Butler CR, Santana I, Bertoux M, Tartaglia MC, Rohrer JD, Poos JM, GENFI Consortium.   +45 more
europepmc   +2 more sources

Structural and functional connectivity in tau mutation carriers: from presymptomatic to symptomatic frontotemporal dementia. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Microtubule‐associated protein tau (MAPT) mutations cause frontotemporal dementia (FTD), characterised by behavioural, language, and motor impairments due to brain connectivity disruptions. We investigated structural and functional connectivity in 86 mutation carriers and 272 controls to map connectivity changes at different ...
Bouzigues A, Du VL, Joulot M, Peysson N, Houot M, Béranger B, Russell LL, Foster PH, Ferry-Bolder E, van Swieten JC, Jiskoot L, Seelaar H, Sanchez-Valle R, Laforce R, Graff C, Galimberti D, Vandenberghe R, de Mendonça A, Tiraboschi P, Santana I, Gerhard A, Levin J, Sorbi S, Otto M, Bertoux M, Lebouvier T, Ducharme S, Butler CR, Ber IL, Finger E, Tartaglia MC, Masellis M, Rowe JB, Synofzik M, Moreno F, Borroni B, Rohrer JD, Migliaccio R, GENetic Frontotemporal dementia Initiative (GENFI).   +38 more
europepmc   +2 more sources

O jogo dos espelhos: autoficção e metaficção em O evangelho segundo a serpente, de Faíza Hayat

Convergência Lusíada
O artigo propõe uma análise do romance português contemporâneo O evangelho segundo a serpente, de Faíza Hayat, tendo por base ideias de teóricos da pós-modernidade acerca da cultura e da produção artística contemporânea, como Zygmunt Bauman, Linda ...
Marcelo Brandão Mattos
semanticscholar   +3 more sources

Pertinence du concept de ‘borne continue’ dans une théorisation des notions aspectuo-temporelles [PDF]

SHS Web of Conferences, 2020
L’aspect grammatical est un opérateur qui actualise une relation prédicative (ou dictum) sur un intervalle topologique d’instants contigus dans un référentiel temporel (continu).
Desclés Jean-Pierre, Guentchéva Zlatka
doaj   +1 more source

Picada de Bothrops (Jararaca) em Pinscher: Relato de caso

Pubvet, 2023
O objetivo do presente relato foi descrever o caso de um canino da raça Pinscher, sete anos e quatro meses de idade, residente no município de Magé, Rio de Janeiro, picado por uma serpente do gênero Bothrops. O acidente ofídico por picada de jararaca em
Veluma Marinho Loli, Gabriele Pereira Corrêa, Letícia Pereira Gonzaga, Julianna de Campos Perez, Kelly de Almeida Aguiar, Thaís Galvão Lins, Marcia Bandeira Nalim   +6 more
doaj   +1 more source

A consciência filosófica na pedagogia histórico-crítica

Revista Histedbr On-line, 2020
Este texto apresenta a íntegra da entrevista com Dermeval Saviani, o formulador originário da pedagogia histórico-crítica (PHC). Ela foi realizada de modo presencial por Marcos Francisco Martins e André Canevalle Rezende, no dia 26 de setembro de 2019 ...
Marcos Francisco Martins, Andre Canevalle Rezende   +1 more
doaj   +1 more source

Extracellular vesicles in the study of Alzheimer's and Parkinson's diseases: Methodologies applied from cells to biofluids

Journal of Neurochemistry, Volume 163, Issue 4, Page 266-309, November 2022., 2022
The isolation of extracellular vesicles from distinct models, including neuronal‐like cell lines as SH‐SY5Y, N2a, primary cultured neurons, astrocytes and microglia and brain tissue, as well from different human or mice biofluids, namely blood, CSF, saliva or urine, can be achieved using several methods. The isolated extracellular vesicles with exosome‐
Margarida Vaz, Tânia Soares Martins, Ana Gabriela Henriques   +2 more
wiley   +1 more source

The Beatles in life sciences: Facts and fictions

Biochemistry and Molecular Biology Education, Volume 50, Issue 3, Page 334-344, May/June 2022., 2022
Abstract The Beatles formed in Liverpool are one of the most famous music groups in the history of pop considered as the best‐selling artists in the category “band,” with the highest amount of claimed record sales. With their foremost pioneering activities in songwriting, artistic presentation, and recording, the band revolutionized many aspects of ...
Ralf Weiskirchen
wiley   +1 more source