Inflammatory and Nested Testicular Sex Cord Tumors: Clinical and Molecular Characterization. [PDF]
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Sertoli–Leydig cell tumor: a clinicopathological analysis in a comprehensive, national cohort
International Journal of Gynecological Cancer, 2023Sertoli-Leydig cell tumors are rare tumors of the ovary. Moderate and poorly differentiated tumors can metastasize and have a poor outcome. A pathogenic variant in DICER1 is associated with an increased risk of developing these tumors along with other clinical phenotypes.
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Sertoli-Leydig cell tumors belong to the group of sex-cord stromal tumors of the ovary. They account for less than 0,5% of all ovarian neoplasms. The majority of these tumors are benign, and almost all are localised unilaterally. Herewith, we describe an ovarian Sertoli-Leydig cell tumor in an 11-year-old girl.
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