Results 31 to 40 of about 1,665,731 (255)

T-SP1: a novel serine protease-like protein predominantly expressed in testis [PDF]

, 2008
Here, we describe a novel member in the group of membrane-anchored chymotrypsin (S1)-like serine proteases, namely testis serine protease 1 (T-SP1), as it is principally expressed in testis tissue.
Geissler, Claudia, Jochum, Marianne, Naegler, Dorit K., Nerlich, Andreas, Neth, Peter, Profanter, Birgit, Sommerhoff, Christian P.   +6 more
core   +1 more source

Nuclear localization of β-catenin in Sertoli cell tumors and other sex cord–stromal tumors of the testis: an immunohistochemical study of 87 cases [PDF]

, 2015
The diagnosis and subclassification of Sertoli cell tumors (SCT) of the testis are often challenging to general surgical pathologists because of the rarity of the tumors. Immunohistochemical study to date has limited diagnostic value.
Ulbright, Thomas M., Zhang, Chen
core   +1 more source

Use of novel serum markers in clinical follow-up of Sertoli-Leydig cell turnours [PDF]

, 2007
Background: Sertoli-Leyclig cell tumours of the ovary account for only 0.2% of malignant ovarian tumours. Two-thirds of all patients become apparent due to the tumour's hormone production. Methods: A 41-year-old patient (gravida 4, para 4) presented with
Campisi P, Ching B, Clinton CW, Dhont M, Emons G, Gershenson DM, O'Hern TM, Prinz RA, Schwartz PE, Tampakoudis P, Young RH, Young RH, Zaloudek C   +12 more
core   +2 more sources

Doxorubicin Affects Testicular Lipids with Long-Chain (C18-C22) and Very Long-Chain (C24-C32) Polyunsaturated Fatty Acids [PDF]

, 2007
Doxorubicin disrupts spermatogenesis by causing apoptosis of spermatogonia and primary spermatocytes. The aim of this study was to examine the effect of this agent on adult rat testicular lipids and their fatty acids.
Aveldaño, Marta Isabel, Maldonado, Eduardo N., Zanetti, Samanta Romina   +2 more
core   +1 more source

Sertoli Cell-Specific Activation of Transforming Growth Factor Beta Receptor 1 Leads to Testicular Granulosa Cell Tumor Formation

Cells, 2023
The transforming growth factor β (TGFβ) superfamily, consisting of protein ligands, receptors, and intracellular SMAD transducers, regulates fundamental biological processes and cancer development.
Xin Fang, Linfeng Nie, Satwikreddy Putluri, Nan Ni, Laurent Bartholin, Qinglei Li   +5 more
doaj   +1 more source

Follistatin-like 3 (FSTL3) mediated silencing of transforming growth factor (TGF ) signaling is essential for testicular aging and regulating testis size [PDF]

, 2013
Follistatin-like 3 (FSTL3) is a glycoprotein that binds and inhibits the action of TGFβ ligands such as activin. The roles played by FSTL3 and activin signaling in organ development and homeostasis are not fully understood.
Abir Mukherjee, Alan L. Schneyer, Andrew A. Pitsillides, Archambeault, Baker, Bakker, Bartholin, Bastow, Besset, Brehm, Chan, Cohen, Cooke, Cooke, Cooke, Coultas, Coussens, Dierich, Do, Fujita, Gill, Hardwick, Itman, Jan Seebacher, Johnston, Judit Villen, Karla J. Oldknow, Kato, Kato, Kooy, Kumar, Lee, Matzuk, Mukherjee, Nef, Noriega, Parvinen, Peter J. O'Shaughnessy, Salisbury, Shang, Sharpe, Sidis, Slegtenhorst-Eegdeman, St-Pierre, Steeno, Steven P. Gygi, Tanimoto, Tapasree Goswami, Tolonen, Tsuchida, Turek, Wilhelm, Wreford, Xia, Yang   +54 more
core   +1 more source

Contribution of recent transgenic models and transcriptional profiling studies to our understanding of the mechanisms by which androgens control spermatogenesis [PDF]

, 2008
Publisher ...
Claessens, Frank, De Gendt, Karel, Denolet, Evi, Saunders, Philippa T K, Sharpe, Richard, Swinnen, Johannes V, Verhoeven, Guido, Willems, Ariane   +7 more
core   +1 more source

Sertoli-Leydig cell tumor of the ovary masquerading as a mucinous adenocarcinoma: a frozen section pitfall

Rare Tumors, 2017
Sertoli-Leydig cells tumors are rare ovarian neoplasms that can be managed with conservative resection given their generally excellent prognosis.
Jonathan E. Zuckerman, Neda A. Moatamed
doaj   +1 more source

Oncologic outcomes following surgical management of clinical stage II sex cord stromal tumors [PDF]

, 2019
Objective To investigate the clinical history of patients with clinical stage II sex cord stromal tumors who underwent RPLND at our institution. Methods Our prospectively maintained testicular cancer database was queried to identify patients who ...
Calaway, Adam C., Foster, Richard S., Masterson, Timothy A., Tachibana, Isamu   +3 more
core   +1 more source

Retiform Sertoli-Leydig Cell Tumor in a 38-Year-Old Woman: A Case Report, Retrospective Review, and Review of Current Literature

Case Reports in Pathology, 2017
Ovarian sex cord-stromal tumors arise from the stromal cells that surround and support the oocytes. Sertoli-Leydig cell tumors belong to this category of ovarian neoplasms.
Laura C. Nwogu, Josh A. Showalter, Suvra Roy, Michael T. Deavers, Bihong Zhao   +4 more
doaj   +1 more source