The effect of metoclopramide treatment on serum prolactin levels, milk composition and yield, and puppy growth rate in bitches during the first week of lactation [PDF]
, 2017 Stefanie Keller
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Journal of Veterinary Medical Research, 2018 FMD virus type A/1/ Egypt 2006 was inactivated with 0.1 M of BEI (Binary ethylene imine) formed by cyclization of 2- Bromoethyl-amine hydrobromide (BEA) in 0.2 N NaoH at 37oC with PH 8.0 for 24 hours.
A. A. Omar +4 more
doaj
Tartrate-Resistant Acid Phosphatase Isoform 5B (TRACP 5B) As Serum Marker of Bone Metastases From Non-Small Cell Lung Cancer (NSCLC) and Breast Cancer. Preliminary Results [PDF]
, 2015 Franco Lumachi +4 more
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Seasonal changes in serum testosterone, 11-ketotestosterone, and 1713-estradiol levels in the brown bullhead, Ictalurus nebuIosus Lesueur [PDF]
, 1984 The seasonal changes in gonadosomatic index (GSI) and strum testosterone, I I-ketotestosterone, and 17&estmdiol levels were measured in adult feral brown bullheads, Ictalurus nebulosus Lzsueur.
Burke, MG, Leatherland, JF, Sumpter, JP
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Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Increased serum levels of procollagen type III peptide in severely injured patients [PDF]
, 1993 Objectives: To determine the serum concentrations of procollagen type in peptide in severely injured patients with different outcomes and to evaluate the relationship between serum procollagen type III peptide concentrations, sources of increased ...
Duswald, Karl-Heimo +6 more
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