Ursodeoxycholic acid improves bilirubin but not albumin in primary biliary cirrhosis: further evidence for nonefficacy. [PDF]
BACKGROUND/AIM: In randomised controlled trials (RCTs) of ursodeoxycholic acid (UDCA), although serum bilirubin is frequently reduced, its effect on disease progression and mortality is unclear.
Burroughs, Andrew K +5 more
core +3 more sources
Free serum cortisol: quantification applying equilibrium dialysis or ultrafiltration and an automated immunoassay system [PDF]
Background: Quantification of bioactive, free serum cortisol concentrations can characterize adrenocortical function more appropriately compared to total serum cortisol measurement.
Briegel, Josef +2 more
core +1 more source
Evaluation of Canine Pancreas-Specific Lipase Activity, Lipase Activity, and Trypsin-Like Immunoreactivity in an Experimental Model of Acute Kidney Injury in Dogs. [PDF]
BackgroundDiagnosis of pancreatitis in dogs is complicated by extrapancreatic disorders that can alter the results of laboratory tests. Extrapancreatic disorders can also affect the diagnosis of exocrine pancreatic insufficiency (EPI).
Cowgill, LD +5 more
core +1 more source
Background Entamoeba gingivalis has been associated with periodontal diseases. Baseline data from the background population, which could help delimit the role of the parasite in health and disease, remain limited.
Christen Rune Stensvold +5 more
doaj +1 more source
Exposure to perfluoroalkyl acids and markers of kidney function among children and adolescents living near a chemical plant. [PDF]
BACKGROUND: Serum levels of perfluorooctanoic acid (PFOA) have been associated with decreased renal function in cross-sectional analyses, but the direction of the association is unclear.
Bartell, Scott M +8 more
core +2 more sources
International efforts in developing a vaccine against Chlamydia trachomatis have highlighted the need for novel immunization strategies for the induction of genital immunity. In this study, we evaluated an intramuscular prime/intranasal boost vaccination
Emma eLorenzen +10 more
doaj +1 more source
Increased incidence of gonorrhoea and chlamydia in Greenland 1990–2012
Background: Since the 1970s, Greenland has presented the highest reported incidence rates of the sexually transmitted infections (STIs) gonorrhoea and chlamydia in the Arctic regions. Objective: This study aims to describe sex- and age-specific incidence
Mila Broby Johansen +5 more
doaj +1 more source
Use of donor serum to prevent passive transfer of hyperacute rejection [PDF]
Organ transplantation in presensitized recipients continues to be contraindicated for heart and kidney recipients due to the risk of hyperacute rejection, which has no known treatment at this time.
Burlingham, William J. +4 more
core +1 more source
Introduction: Emerging evidence suggests that vaccines, in addition to their disease-specific effects, have important non-specific effects (NSEs), which contribute to their overall effect on mortality and morbidity.
Christine Stabell Benn +4 more
doaj +1 more source
Increased transmissibility of SARS-CoV-2 lineage B.1.1.7 by age and viral load
Establishing the relative transmissibility of emerging variants of SARS-CoV-2 is key for pandemic management. Here, the authors use full-population administrative data from Denmark linked to PCR test results and estimate that the Alpha variant was ~60 ...
Frederik Plesner Lyngse +14 more
doaj +1 more source

