Results 61 to 70 of about 5,363,269 (308)

State of Harmonization of 24 Serum Albumin Measurement Procedures and Implications for Medical Decisions [PDF]

, 2017
BACKGROUND: Measurements of serum and plasma albumin are widely used in medicine, including as indicators of quality of patient care in renal dialysis centers.
Bachmann, Lorin M., Boyd, James C., Bruns, David E., Miller, W. Greg, Yu, Min   +4 more
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Molecular identification of the ompL1 gene within Leptospira interrogans standard serovars

Journal of Infection in Developing Countries, 2014
Introduction: Leptospirosis, caused by infection with pathogenic Leptospira species, is one of the most prevalent zoonotic diseases in the world. Current leptospiral vaccines are mainly multivalent dead whole-cell mixtures made of several local dominant ...
Mehrangiz Dezhbord, Majid Esmaelizad, Pejvak Khaki, Fariba Fotohi, Athena Zarehparvar Moghaddam   +4 more
doaj   +1 more source

Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease [PDF]

, 2019
Neurofilament light chain (NfL) is a promising fluid biomarker of disease progression for various cerebral proteopathies. Here we leverage the unique characteristics of the Dominantly Inherited Alzheimer Network and ultrasensitive immunoassay technology ...
Allegri, Ricardo, Alzheimer Network, Amtashar, Fatima, Apel, Anja, Barro, Christian, Bateman, Randall, Bateman, Randall J., Benzinger, Tammie, Benzinger, Tammie L. S., Berman, Sarah, Bodge, Courtney, Brandon, Susan, Brooks, William, Buck, Jill, Buckles, Virginia, Chea, Sochenda, Chhatwal, Jasmeer, Chhatwal, Jasmeer, Chrem, Patricio, Chui, Helena, Cinco, Jake, Clifford, Jack, Cruchaga, Carlos, DiBari, Siri Houeland, Donahue, Tamara, Douglas, Jane, D’Mello, Mirelle, Edigo, Noelia, Erekin-Taner, Nilufer, Fagan, Anne, Fagan, Anne M., Farlow, Marty, Farrar, Angela, Feldman, Howard, Flynn, Gigi, Fox, Nick, Franklin, Erin, Fujii, Hisako, Gant, Cortaiga, Gardener, Samantha, Ghetti, Bernardino, Ghetti, Bernardino, Goate, Alison, Goate, Alison M., Goldman, Jill, Gordon, Brian, Gordon, Brian A., Graff-Radford, Neill, Graff-Radford, Neill R., Gray, Julia, Gräber, Susanne, Gurney, Jenny, Hassenstab, Jason, Hirohara, Mie, Holtzman, David, Hornbeck, Russ, Ikeuchi, Takeshi, Ikonomovic, Snezana, Jerome, Gina, Jucker, Mathias, Jucker, Mathias, Kaeser, Stephan A., Karch, Celeste, Kasuga, Kensaku, Kawarabayashi, Takeshi, Klunk, William, Koeppe, Robert, Kuder-Buletta, Elke, Kuder-Buletta, Elke, Kuhle, Jens, LaFougere, Christian, Laske, Christoph, Laske, Christoph, Lee, Jae-Hong, Levin, Johannes, Levin, Johannes, Marcus, Daniel, Martins, Ralph, Martins, Ralph, Mason, Neal Scott, Masters, Colin, Masters, Colin L., Maue-Dreyfus, Denise, McDade, Eric, McDade, Eric M., Montoya, Lucy, Mori, Hiroshi, Morris, John, Morris, John C., Nagamatsu, Akem, Neimeyer, Katie, Noble, James, Noble, James M., Norton, Joanne, Perrin, Richard, Preische, Oliver, Raichle, Marc, Ringman, John, Ringman, John M., Roh, Jee Hoon, Rossor, Martin N., Salloway, Stephen, Salloway, Stephen, Schofield, Peter, Schofield, Peter R., Schultz, Stephanie A., Shimada, Hiroyuki, Shiroto, Tomoyo, Shoji, Mikio, Sigurdson, Wendy, Sohrabi, Hamid, Sparks, Paige, Suzuki, Kazushi, Swisher, Laura, Taddei, Kevin, Vöglein, Jonathan, Wang, Guoqiao, Wang, Jen, Wang, Peter, Weiner, Mike, Wolfsberger, Mary, Xiong, Chengjie, Xu, Xiong   +122 more
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Molecular characterization and epidemiology of Streptococcus pneumoniae serotype 8 in Denmark

BMC Infectious Diseases, 2021
Background Streptococcus pneumoniae serotype 8 incidence has increased in Denmark after the introduction of pneumococcal conjugated vaccines (PCV). The mechanism behind the serotype 8 replacement is not well understood. In this study, we aimed to present
Camilla Bülow Hansen, Kurt Fuursted, Palle Valentiner-Branth, Tine Dalby, Charlotte Sværke Jørgensen, H-C Slotved   +5 more
doaj   +1 more source

Effect of Oocyte Vitrification Before and After in Vitro Maturation Towards Bcl-2, Bax and Bcl-2/Bax Ratio Expression [PDF]

, 2016
Objectives: to compare the expression of Bcl-2, Bax and Bcl-2/Bax ratio in cumulus cell and oocyte between vitrified oocyte pre and post in vitro maturation.Materials and Methods: Maturation was operated in medium TC 100 µl for 24 hours.
Aswin, H. (Haryanto), Faizah, Z. (Zakiyatul), Lunardhi, H. (Hamdani)   +2 more
core  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

In vitro effect of subinhibitory concentrations of ceftazidime and meropenem on the serum sensitivity of Pseudomonas aeruginosa strains [PDF]

, 2007
The aim of this study was to determine the effect of subminimal inhibitory concentrations (subMICs) of ceftazidime, meropenem and gentamicin on the in vitro serum sensitivity of Pseudomonas aeruginosa strains isolated from a variety of isolation sites at
Bedenić, Branka, Drenjančević, Domagoj, Vraneš, Jasmina, Šakić-Zdravčević, Katarina   +3 more
core   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source