Results 171 to 180 of about 1,546,756 (303)

Serum Alkaline Phosphatase in Cryptogenic Stroke Cases with Active Cancer. [PDF]

open access: yesIntern Med, 2022
Izumi T   +4 more
europepmc   +1 more source

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng   +7 more
wiley   +1 more source

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

open access: yesHepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso   +16 more
wiley   +1 more source

Prognostic values of serum alkaline phosphatase and globulin levels in patients undergoing intravenous thrombolysis. [PDF]

open access: yesFront Mol Neurosci, 2022
Zhu HJ   +8 more
europepmc   +1 more source

A UBE3A‐UTX Proteostasis‐Epigenetic Axis Governs Hypothalamic Energy Homeostasis

open access: yesAdvanced Science, EarlyView.
Ubiquitin protein ligase E3A (UBE3A) regulates hypothalamic energy homeostasis and promotes degradation of the histone demethylase UTX (KDM6A). Neuronal UBE3A loss increases susceptibility to diet‐induced obesity and is accompanied by UTX accumulation, reduced histone H3 lysine 27 trimethylation, and altered endoplasmic reticulum stress‐responsive gene
Junekyoung Lee   +7 more
wiley   +1 more source

Nicotinamide riboside and pterostilbene reduces markers of hepatic inflammation in NAFLD: A double‐blind, placebo‐controlled clinical trial

open access: yesHepatology, EarlyView., 2022
NRPT 1X reduces ALT and ceramide 14:0 in 65% of subjects as compared to only 28% in the placebo group. Abstract Background and Aims The prevalence of NAFLD is increasing globally and on a path to becoming the most frequent cause of chronic liver disease. Strategies for the prevention and treatment of NAFLD are urgently needed.
Ryan W. Dellinger   +7 more
wiley   +1 more source

NOTES ON THE DECOMPOSITION OF PARATHION IN LIVING OPGANISMS : Ⅲ. SERUM PARATHION SPLITTING ACTIVITY AND SERUM ALKALINE PHOSPHATASE

open access: yes
The variation of serum parathion-splitting activity and serum alkaline phosphatese in the dogs poisoned with varied amounts of parathion and KDTP was studies to examine the similarity of those enzymes.
Iuchi, Iwao
core  

Serum alkaline phosphatase in infants with obstructive jaundice: Relation to vitamin D supplementation

open access: yes, 1973
Serum alkaline phosphatase total activity was determined in infants with biliary atresia,in infants with hepatitis, and in normal control infants. Values ranged from normal to significantly elevated in infants with biliary atresia and in those with ...
Bastis-Maounis, B.   +2 more
core  

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