Results 251 to 260 of about 1,687,679 (297)

PROTAC‐Engineered Protein/DNA Nanoantigen is a Potent Booster for Dendritic Cell Vaccines in Cancer Immunotherapy

Advanced Science, EarlyView.
A PROTAC‐functionalized protein/DNA‐integrated nanoantigen platform is developed to enhance dendritic cell vaccine potency. By combining a VHL‐recruiting peptide‐modified antigen with a sustained expression plasmid within CaCO3 nanoparticles, this system amplifies cross‐presentation, promotes DC maturation, and elicits robust Th1 and CTL responses ...
Peng Liu, Qiang Chen, Zhe Zhou, Yuekang Xu, Jinyao Li   +4 more
wiley   +1 more source

Evidence-Based Guidelines for the Diagnosis and Treatment of Pediatric CKD-Mineral and Bone Disorder (Version 2024). [PDF]

Kidney Int Rep
Wang M, Xiong HY, Zhu C, Yu X, Jiao J, Tan L, Shen Y, Xu H, Mao J, Zhou J, Jiang XY, Shen Q, Wang F, Huang S, Huang W, Xia ZK, Liu XR, Wang H, Wu YB, Yu L, Tao YH, Gao CL, Li YJ, Sun SZ, Zhang DF, Shao XS, Zhao LJ, Wang X, Dang XQ, Huang HM, Chen Y, Li Q, Zhang AH, Subspecialty Group of Nephrology, the Society of Pediatrics, Chinese Medical Association.   +35 more
europepmc   +1 more source

Polystyrene Nanoplastics Drive β‐Cell Dedifferentiation Through Dendritic Cell‐Intrinsic MHC‐I‐Dependent Inflammatory Crosstalk

Advanced Science, EarlyView.
Polystyrene nanoplastics disrupt pancreatic immune–endocrine homeostasis by promoting MHC‐I‐associated dendritic cell activation and inflammatory crosstalk with β cells. This immune remodeling drives β‐cell dedifferentiation, impairs insulin secretion, and aggravates metabolic dysfunction, revealing a previously unrecognized immunometabolic mechanism ...
Conghui Qiao, Yuqing Song, Fang Yang, Menghui Guo, Libin Jiang, Xiaoyue Quan, Wei Wei, Xinyang Wang, Tianshu Han, Mingyuan Liu, Wenbo Jiang   +10 more
wiley   +1 more source

Evaluating the Influence of Flaxseed Oil Against Docosahexaenoic Acid on Cancer Antigen CA15-3, Biochemical and Histopathological Parameters of DMBA-Induced Mammary Tumors Female Albino Wistar Rats. [PDF]

Food Sci Nutr
Aza HN, Djikeng FT, Ufuan AA, Fotsing IS, Zingue S.   +4 more
europepmc   +1 more source

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Dietary Supplementation with <i>Zanthoxylum bungeanum</i> Seed Cake and Meal Improves the Productive Performance and Antioxidant Capacity of Laying Hens. [PDF]

Animals (Basel)
Cao S, Lin H, Li X, Li X, Zhao J, Liu J.
europepmc   +1 more source

Effect of dietary chenodeoxycholic acid on fat deposition and intestinal health in Wenchang chickens. [PDF]

Poult Sci
Ouyang K, Xuan T, Chen T, Sun L, Wang X, Liu Q, Liu J, Xi Q, Wei L, Zhang Y.   +9 more
europepmc   +1 more source

Executive Summary of Evidence-Based Guidelines for the Diagnosis and Treatment of Pediatric CKD-Mineral and Bone Disorder (Version 2024). [PDF]

Kidney Int Rep
Wang M, Xiong HY, Zhu C, Yu X, Jiao J, Tan L, Shen Y, Xu H, Mao J, Zhou J, Jiang XY, Shen Q, Wang F, Huang S, Huang W, Xia ZK, Liu XR, Wang H, Wu YB, Yu L, Tao YH, Gao CL, Li YJ, Sun SZ, Zhang DF, Shao XS, Zhao LJ, Wang X, Dang XQ, Huang HM, Chen Y, Li Q, Zhang A, Subspecialty Group of Nephrology, the Society of Pediatrics, Chinese Medical Association.   +35 more
europepmc   +1 more source

Bifidobacterium Pseudolongum-Derived Inosine Mitigates Polystyrene Nanoplastics-Induced Hepatic Injury by Inhibiting the Polarization of M1 Macrophages. [PDF]

Adv Sci (Weinh)
Zhang K, Chen Y, Wan J, Yang J, Chen L, Li Q, Zhou A, Zhou N, Ding J, Wang Q, Sun J.   +10 more
europepmc   +1 more source

Association between candidate genes and FRAX scores in postmenopausal women. [PDF]

Endocrine
Pepe J, Viviani A, Cipriani C, Ciminelli BM, Jodice C, Colangelo L, Forti M, Santori R, Terreri S, Minisola S, Latini S, Occhiuto M, Malaspina P, Novelletto A.   +13 more
europepmc   +1 more source