Results 71 to 80 of about 1,687,679 (297)

Body mass index is not a predictor of biochemical recurrence after radical prostatectomy in Dutch men diagnosed with prostate cancer [PDF]

open access: yes, 2010
Contains fulltext : 95677.pdf (Publisher’s version ) (Open Access)PURPOSE: To determine the effect of body mass index (BMI) on clinical and pathological characteristics at time of diagnosis and on risk of biochemical recurrence after ...
van Roermond, J.G.   +37 more
core   +2 more sources

Indexing serum biochemical attributes ofLutjanus argentimaculatus(Forsskal, 1775) to instrument in health assessment

open access: yesAquaculture Research, 2020
The present study was aimed to establish reference data for nine serum biochemical attributes (glucose, protein, albumin, globulin, albumin/globulin ratio, cholesterol, triglycerides, serum glutamate oxaloacetate transaminase [SGOT] and serum glutamate pyruvate transaminase [SGPT]) of a supreme aquaculture candidate, namely Lutjanus argentimaculatus ...
Kalarical Janardhanan Reshma   +6 more
openaire   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Effect of compound acidifier on growth performance, serum biochemical indexes antioxidant capacity and intestinal morphology of broilers

open access: yesSiliao yanjiu, 2022
The experiment was to study the effect of compound acidifier on broiler diet. A total of 1 200 AA white-feathered broilers hatched in the same batch with half in male and female were randomly divided into three groups, with eight replicates in each group
Xiao-liang WANG   +6 more
doaj  

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

Effect of compound Chinese medicine preparation on serum biochemical indexes and production performance of heat stress sows

open access: yesSiliao yanjiu, 2022
The experiment was to investigate the effect of Yupingfeng granules on serum biochemical indexes and production performance of sows under heat stress. 75 healthy sows (Landrace × Yorkshire) with the gestation of 107 d and with the similar body weight ...
Yi-hao MO   +7 more
doaj  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Quality of cellulase silage corn stover and its effect on growth performance of beef cattle

open access: yesSiliao yanjiu, 2022
The experiment was to explore the effect of EN on corn stover silage quality, beef cattle growth performance, antioxidant capacity and immunity. CK group was set in experiment, and the amount of EN added in each treatment group was 100 (EN1 group), 200 ...
CHE Lei-jie, HAO Wang-bao
doaj  

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

open access: yesMolecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba   +5 more
wiley   +1 more source

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