Results 101 to 110 of about 926,436 (268)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

The investigation of Servant Leadership on Organizational Trust and Empowerment in Public Organizations [PDF]

مدیریت دولتی, 2009
Public interests justify the existence of public administration and public administrator must obligate it in any policies and decisions. Reduction of public trust and organizational trust in recent years and necessity of power distribution and ...
Aryan Gholipour, Ali Asghar Pourezzat, Mahmood Hazrati   +2 more
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Servant Leadership, Adult Development, and the Inner Development Goals

Servant leadership focuses on the well-being of those being served, helping them become healthier, wiser, freer, and more autonomous. The emphasis on becoming implies inner development.
Stålne, Kristian, Stålne, Kristian,, Reams, Jonathan,, Reams, Jonathan, van Dierendonck, Dirk; id_orcid, van Dierendonck, Dirk,   +5 more
core   +1 more source

Job Satisfaction and the Priority of Valuing People

SAGE Open, 2017
The servant leadership literature has a growing body of evidence pointing to the positive relationship between servant leadership and job satisfaction. Because many of these studies have focused on quantitative analyses of the subject, the present study ...
Michael E. McNeff, Justin A. Irving
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Personality traits and personal values of servant leaders

, 2019
Purpose: Servant leaders focus on their direct reports to enable them to grow to be independent and autonomous leaders. The purpose of this paper is to understand the way personal values and personality traits collectively influence this other-centered ...
Sun, P, Shang, S
core   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

The nexus between servant leadership and organizational citizenship behavior through the mediating role of perceived organizational politics in Ethiopian federal public service organizations

Cogent Business & Management
This is a study about the servant leadership-organizational citizenship behavior debate aimed at examining the effect of servant leadership on organizational citizenship behavior through the mediating effect of perceived organizational politics.
Addisu Debalkie Demissie, Abebe Ejigu Alemu, Assefa Tsegay Tensay   +2 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source