Landscape of BRAF transcript variants in human cancer
Molecular Oncology, EarlyView.We investigate the annotation of BRAF variants, focusing on protein‐coding BRAF‐220 (formerly BRAF‐reference) and BRAF‐204 (BRAF‐X1). The IsoWorm pipeline allows us to quantify these variants in human cancer, starting from RNA‐sequencing data. BRAF‐204 is more abundant than BRAF‐220 and impacts patient survival.
Maurizio S. Podda +5 more
wiley +1 more source
Methodology and pilot implementation of modular educational-development platform for Interoperable Digital Twin. [PDF]
Sci RepPajpach M +4 more
europepmc +1 more source
Designing a Kanban manufacturing system using the server network generator (SNG) CASE tool [PDF]
, 1991 A. Bouchentouf-Idriss, Lawrence Zeidner
openalex +1 more source
TRPM8 levels determine tumor vulnerability to channel agonists
Molecular Oncology, EarlyView.TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo +18 more
wiley +1 more source
Post-Quantum Secure Multi-Factor Authentication Protocol for Multi-Server Architecture. [PDF]
Entropy (Basel)Wen Y, Su Y, Li W.
europepmc +1 more source
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
Incentive mechanism of foundation model enabled cross-silo federated learning. [PDF]
Sci RepZhang N, Xu X, Liu X, Wu J, Tang H.
europepmc +1 more source
Serial Electrocardiographic Changes During Long-Term Treatment of Server Hypertension with Minoxidil
, 1980 Donald Hall, K. L. Froer, W Rudolph
openalex +1 more source
Finiteness of Waiting-Time Moments in General Stationary Single-Server Queues [PDF]
, 1992 D. J. Daley, Tomasz Rolski
openalex +1 more source
Molecular Oncology, EarlyView.The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song +11 more
wiley +1 more source