Results 211 to 220 of about 779,994 (339)
DeepMolecules: a web server for predicting enzyme and transporter-small molecule interactions. [PDF]
Kroll A+3 more
europepmc +1 more source
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
In-silico study: Hm86 protein of Hyalomma marginatum (Ixodida) as a candidate to provide anti-tick vaccine. [PDF]
Shahriari-Namadi M, Azizi K, Alipour H.
europepmc +1 more source
Non‐small cell lung cancer targeted treatment is limited to a few known genetic alterations, with few alternatives in advanced treatment lines. To direct treatment decisions by drug sensitivity testing (DST), this study compared several methods for tumor cell isolation from malignant effusions, pointing to repeated CD45+ cell depletion for effective ...
Navit Mooshayef+10 more
wiley +1 more source
Prediction and quality assessment of protein quaternary structure models using the MultiFOLD2 and ModFOLDdock2 servers. [PDF]
McGuffin LJ+5 more
europepmc +1 more source
Nearly optimal control of queues in heavy traffic with heterogeneous servers
Kandethody M. Ramachandran
openalex +2 more sources
Carcinoma‐associated fibroblasts (CAFs) in tumors influence cancer progression. We identified endoglin (ENG) as a key factor in TGF‐β signaling in myofibroblastic CAFs (myCAFs), linked to poor breast cancer outcomes. Inhibiting ENG on myCAFs suppressed the TGF‐β‐Smad2/3 pathway, reducing primary tumor growth and metastasis.
Shoki Okubo+11 more
wiley +1 more source
ASOptimizer: optimizing chemical diversity of antisense oligonucleotides through deep learning. [PDF]
Kang S, Lee D, Hwang G, Lee K, Kang M.
europepmc +1 more source