Results 231 to 240 of about 1,718,808 (353)

The HADDOCK2.2 Web Server: User-Friendly Integrative Modeling of Biomolecular Complexes.

open access: yesJournal of Molecular Biology, 2016
G. V. Zundert   +9 more
semanticscholar   +1 more source

MicroRNAs in seminal plasma are able to discern infertile men at increased risk of developing testicular cancer

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1188-1202, April 2025.
Male infertility is a known risk factor for the development of testicular cancer. In this paper, we analyzed the expression profile of a microRNA panel by real‐time PCR and validated the results by digital PCR. Experimental and bioinformatics analyses allowed us to identify possible biomarkers able to discern men with a higher risk of developing ...
Carmen Ferrara   +14 more
wiley   +1 more source

Detection rate for ESR1 mutations is higher in circulating‐tumor‐cell‐derived genomic DNA than in paired plasma cell‐free DNA samples as revealed by ddPCR

open access: yesMolecular Oncology, EarlyView.
Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou   +11 more
wiley   +1 more source

Maize’s origin to be revisited

open access: yesPlant Signaling & Behavior
Khaled Moustafa
doaj   +1 more source

Multi‐omics profiling reveals key factors involved in Ewing sarcoma metastasis

open access: yesMolecular Oncology, Volume 19, Issue 4, Page 1002-1028, April 2025.
Using a mouse model that recapitulates the spread of tumor cells within the body, we have profiled paired tumors and metastasis samples using a multiomics approach combining different layers of biological information. We identified key genes that drive metastasis in Ewing sarcoma.
Mariona Chicón‐Bosch   +11 more
wiley   +1 more source

Robust acute myeloid leukemia engraftment in humanized scaffolds using injectable biomaterials and intravenous xenotransplantation

open access: yesMolecular Oncology, Volume 19, Issue 5, Page 1371-1385, May 2025.
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa   +13 more
wiley   +1 more source

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