Results 71 to 80 of about 313,043 (218)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
FEBS Letters, EarlyView.This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Considering Interactions among Multiple Criteria for the Server Selection
Journal of Information and Organizational Sciences, 2010 Decision-making about server selection is one of the multi-criteria decision-making (MCDM) processes where interactions among criteria should be considered.
Vesna Čančer
doaj
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Clinical OphthalmologyIngeborg Stalmans,1,2 Christophe Baudouin,3,4 Jose Manuel Larrosa,5 Stefanie Schmickler,6 Francesco Oddone,7 Yosuf El-Shabrawi,8 Gerhard Garhoefer,9 Georg Mossboeck,10 Ingeborg Stalmans,11 Kuldar Kaljurand,12 Kai Noor Silmakabinet,13 Tia Jugaste,14 Kai ...
Stalmans I +4 more
doaj
WLAN Integrated with GPRS Network Securely
Al-Khawarizmi Engineering Journal, 2012 In this paper a WLAN network that accesses the Internet through a GPRS network was implemented and tested. The proposed network is managed by the Linux based server.
Mohammed A. Abdalla +2 more
doaj
MACRO SYNTHESIS OF WIDE AREA COMPUTER NETWORKS AT NONLINEAR COSTS
Journal of Engineering Science (Chişinău)In practice, simple solutions of quick preliminary estimation of basic characteristics of a wide area computer network sometimes are needed. To achieve this goal, the backbone data transfer subnet and server set of computer networks are opportune to ...
BOLUN, Ion
doaj +1 more source
The Possibilities of WWW Utilization for Process Control [PDF]
Acta Montanistica Slovaca, 1999 The contribution deals with the possibilities of www technology utilization in real time process control and describes the representation of this information on client site in the www page form.
Roškanin Martin, Horovčák Pavel
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source