Advanced Science, EarlyView.RLIM‐mediated SLC7A11 polyubiquitination is required for SPTBN2‐mediated trafficking and membrane localization of SLC7A11, which enables oligodendrocyte precursor cells to be resistant to ferroptosis and safeguards oligodendrocyte lineage progression and thus myelination.
Yuwei Li +8 more
wiley +1 more source
Do students' attitudes toward required readings and service-learning for a Medical Humanities course predict their perception of whether the course fosters their personal and professional development? [PDF]
Front Med (Lausanne)Rogers SL, Van Winkle LJ.
europepmc +1 more source
Advanced Science, EarlyView.Large‐scale UK Biobank analyses identify clinical and proteomic signatures for early prediction of valvular heart disease and its subtypes. Proteins add predictive value for VHD, AVS, and MVR, with outcome‐specific compact panels showing translational potential. Multi‐layer evidence highlights matrix remodeling, protease regulation, immune inflammation,
Zhihao Jiang +10 more
wiley +1 more source
Benefits of musculoskeletal health promotion in school communities through service-learning: a mixed-method approach. [PDF]
Front Public HealthCalvo S +5 more
europepmc +1 more source
Arterial Blood‐Mediated Deep‐Tissue Photoacoustic Oximetry
Advanced Science, EarlyView.The arterial prior method (APM+) for photoacoustic oximetry is introduced, which leverages the high arterial blood oxygenation to calibrate the fluence at the artery and estimate the oxygenation of the surrounding tissue, thus circumventing the spectral coloring problem. APM+’s accuracy and consistency are shown in a series of phantom and in vivo human
Karteekeya Sastry +7 more
wiley +1 more source
RHINO: An Integrative Multi‐Omics Framework Linking Circadian Physiology to Precision Medicine
Advanced Science, EarlyView.RHINO (RHythmic Interacting Network for multi‐Omics) is an integrative framework that maps circadian regulation across diverse genetic and disease contexts and prioritizes druggable circadian targets. Released as an AI‐powered interactive web portal, RHINO unifies genetic, regulatory, disease, and drug–target information, enabling context‐specific ...
Ying Chen +12 more
wiley +1 more source
Impact of a Service Learning Curriculum that Emphasizes Bidirectional Learning on Medical Students' Professional Identity Formation. [PDF]
Med Sci EducKovaric K, Luk J.
europepmc +1 more source
Advanced Science, EarlyView.The microalgae‐nanoparticle hybrid system with antibacterial activity can improve the oral delivery and therapeutic efficiency for hepatic encephalopathy treatment. Oral administration of the system can reduced systemic ammonia levels, enhanced intestinal barrier function, attenuated systemic and neuroinflammation, ameliorated cognitive impairments ...
Kaiyue Wang +8 more
wiley +1 more source
Training Socially-Conscious Dentists: Development and Integration of Community Service-Learning in Dental Curricula in Ontario, Canada. [PDF]
Int Dent JJessani A +7 more
europepmc +1 more source
Advanced Science, EarlyView.This perspective contrasts the historical, linear progression of early AI with the dynamic, iterative nature of AI 4.0; and it describes the real‐world medical applications and the necessary evolution of laboratory infrastructure brought about by AI 4.0.
Weida Liu, Gary Peltz
wiley +1 more source