Results 131 to 140 of about 11,676,712 (286)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

The XLVIIIth International Congress of City and Regional Planners. ISOCARP 2012 (September 10-13, 2012)

open access: yesПроект Байкал, 2013
- Press Service of the ISOCARP Congress 2012
doaj   +1 more source

Beyond conventional service economics: utility services, service-product chains, and job services [PDF]

open access: yes, 2000
This essay intends to explore three innovative ways to foster job creation in services: First, the switch from product markets to utility markets would induce more and new types of user services. Such a switch would not only be more employment friendly but also foster a sustainable economic development compatible with ecological principles.
openaire   +2 more sources

Building on the value of Victoria’s community sector [PDF]

open access: yes
Building on the value of Victoria’s community sector goes beyond the sector’s economic contribution. It discusses the value of all Victoria’s community sector organisations, including those operating with registered charitable status and those ...
Victorian Council of Social Service
core  

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Like Looking for the Soul in a Test Tube: The Banal Corruptions of ‘Measuring Man’ in the New Age of Public Media

open access: yesMedijske Studije, 2015
It has become common place to suggest that the concept and institutions of public service broadcasting (PSB) are being fundamentally challenged by new technologies, new politics and new economics. Out of these challenges, in a kind of noble optimism, has
Michael Tracey
doaj  

Strengthening the state: a snapshot of Victoria’s community sector charities [PDF]

open access: yes
Victoria’s community sector organisations make a significant contribution to strengthening the state’s economy and society. They generate high levels of economic activity, employment and volunteer support.
Victorian Council of Social Service
core  

Working Report #1: Service Model Accessibility (Service Provider Perspectives) [PDF]

open access: yes, 2009
This report examines the differences in service accessibility across central, integrated, and school/community based child welfare service delivery models including geographic proximity to families, acceptability of the setting to families, and ...
Cameron, Gary, Hazineh, Lirondel
core   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Unions and Upward Mobility for Service-Sector Workers [PDF]

open access: yes
This report uses national data from the Current Population Survey (CPS) to show that unionization raises the wages of the typical service sector worker by 10.1 percent compared to their non-union peers.
John Schmitt
core  

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