Results 21 to 30 of about 6,920,344 (259)

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Rethinking Service Companies’ Business Logic: Do We Need a Customer-Dominant Logic as a Guideline? [PDF]

, 2009
Purpose –This paper explores and expands the roles of customers and companies in creating value by introducing a new a customer-based approach to service. The customer’s logic is examined as being the foundation of a customer-based marketing and business
Sundström, E,, Sundström, Erik, Kristina Heinonen, Erik Sundström, Heinonen, Kristina, Mickelsson, Karl-Jacob, Andersson, Per,, Edvardsson, Bo, Per Andersson, Strandvik, Tore, Karl‐Jacob Mickelsson, Edvardsson, B,, Strandvik, T,, Sundström, Erik,, Heinonen, K,, Andersson, Per, Tore Strandvik, Bo Edvardsson, Edvardsson, Bo,, Mickelsson, K-J,   +19 more
core   +1 more source

Challenges of Undertaking Research in Rural Areas of Ghana: The Influence of Geographical Factors

Journal of Rural and Community Development, 2017
Research in rural areas in developing countries such as Ghana is affected by various challenges. A number of these challenges are geographical in character and need to be factored into the research design to minimize costs, delays, data inadequacies and ...
Service Opare
doaj  

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Use of EZProxy to access international journals among students of Library and Information Science, University of Indonesia

Record and Library Journal, 2016
Student’s magister is one of user library university of Indonesia those who need information regarding duty as carried out college.  With different backgrounds students as, made they need facilities sources of information easy and efficient.
Rusdiyah Ciptaning Dwi Kusuma
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Real-world pharmacoclinical implementation of risdiplam under a national SMA protocol: A hospital pharmacy registry-based case series

Pakistan Journal of Pharmaceutical Sciences
Background: Spinal muscular atrophy (SMA) is a rare neuromuscular disorder treated with disease-modifying therapies such as risdiplam. In Spain, its use is regulated by a national pharmacoclinical protocol that requires structured monitoring. Objectives:
Roberto Lozano, Aragn Health Service, Zaragoza, Spain   +3 more
doaj   +1 more source

Pengembangan Framework Sistem Informasi Antrian pada Student Service Center Binus University

ComTech, 2014
Queues can be found in all aspects of life, especially in the service industry, including at Binus University in the Student Service Center. Sizeable number of students at certain arrival time, has led to a long queue and this affects student discomfort
Reina Reina, Josef Bernadi Gautama
doaj   +1 more source