Results 101 to 110 of about 836,778 (261)

Readiness for non-communicable disease service delivery in Ethiopia: an empirical analysis

BMC Health Services Research
Background Ethiopia’s health system is overwhelmed by the growing burden of non-communicable diseases (NCDs). In this study, we assessed the availability of and readiness for NCD services and the interaction of NCD services with other essential and non ...
Azeb Gebresilassie Tesema, Rohina Joshi, Seye Abimbola, Alemnesh H. Mirkuzie, Daria Berlina, Tea Collins, David Peiris   +6 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Ambulance routing optimization based on emergency medical service availability

Discover Artificial Intelligence
Ambulance routing optimization has been in the spotlight in recent years. Researchers have tried to modify traditional vehicle routing problems to model and examine real-world logistics and transportation-related problems. In the healthcare sector, being
Mona Almalki, Eman Aldhahri, Nahla Aljojo   +2 more
doaj   +1 more source

Service availability and readiness of malaria surveillance information systems implementation at primary health centers in Indonesia. [PDF]

PLoS One, 2023
Herawati MH, Besral, Lolong DB, Pracoyo NE, Sukoco NEW, Supratikta H, Veruswati M, Asyary A.   +7 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Family planning service availability and readiness assessment of primary health care facilities in Delta State, Nigeria: a mixed methods survey. [PDF]

Reprod Health, 2023
Obong DT, Oyibo P.
europepmc   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Service availability and readiness for basic emergency obstetric and newborn care: Analysis from Nepal Health Facility Survey 2021. [PDF]

PLoS One, 2023
Pandey AR, Adhikari B, Lamichhane B, Joshi D, Regmi S, Lal BK, Dahal S, Baral SC.   +7 more
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Communicable and Non-communicable Diseases Diagnosis and Treatment Service Availability at Primary Health Care Units During COVID-19 Outbreak in Ethiopia. [PDF]

Ethiop J Health Sci, 2023
Gonete TZ, Asseffa NA, Gashu KD, Tilahun B, Angaw DA, Jisso M, Tamiso A, Alemayehu A, Fikre R, Abdisa B, Sime H, Yesuf EA, Umer A, Kebede M, Mohammed H, Yazie B, Gurmu KK, Endehabtu BF.   +17 more
europepmc   +1 more source