Results 61 to 70 of about 2,238,869 (292)

Project management: a new service delivery paradigm

Koers : Bulletin for Christian Scholarship, 2007
In line with international trends in governance, the South African Government’s initial focus on the development of policy frameworks, structures and systems in order to give effect to the values and principles of the Constitution, shifted to the most ...
G. van der Walt
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Analisis Delivery Service Pada Bakmi GM [PDF]

, 2008
In the fast growing and expanding market of Bakmi GM, and also to give better service to the customer, since 2003 Bakmi GM has added Delivery Service. Bakmi GM needed evaluation for the running system also re – engineer of the system to improve service ...
Laura, Sutiswan, Prima, Yulianto
core  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Recovery of threatened plant species and their habitats in the biodiversity hotspot of the Southwest Australian Floristic Region

Plant Diversity, 2019
The Southwest Australian Floristic Region (SWAFR) is a global biodiversity hotspot with high plant diversity and endemism and a broad range of threatening processes. An outcome of this is a high proportion of rare and threatened plant species.
Leonie Monks, Sarah Barrett, Brett Beecham, Margaret Byrne, Alanna Chant, David Coates, J. Anne Cochrane, Andrew Crawford, Rebecca Dillon, Colin Yates   +9 more
doaj   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Proceedings of essential health care package development, in Botswana and Sierra Leone, November 2022

BMC Proceedings
The development of essential health care package (EHCP) has been recognized as a critical tool for guiding country level actions towards Universal Health Coverage (UHC).
Humphrey Cyprian Karamagi, Solyana Ngusbrhan Kidane, Pierre Claver Kariyo, Araia Berhane Mesfin, Isabella Maina, Gertrude Avortri, Hyppolite Kalambay Ntembwa   +6 more
doaj   +1 more source

Databases in the Management of Epidemiological Outbreaks Part of the National Critical Infrastructure: The Evolution during the Pandemic

Applied Medical Informatics, 2021
The evolution of the pandemic has led to a change in public health and data management in the infectious disease surveillance network monitored by the county public health directorates.
Călin MUNTEAN, Călin CHEŢE, Alexandru BULLA, Alexandru POPA   +3 more
doaj  

Qualitative investigation of the role of collaborative football and walking football groups in mental health recovery [PDF]

, 2017
Efforts to increase physical activity levels in people with serious mental health conditions are viewed as desirable but little is known about how best to support this group to engage in exercise over extended periods.
Dickens, Geoffrey L., Harris, John, Kerin, Tracey, Lamont, Emma, McDonald, Gill   +4 more
core   +3 more sources