Results 121 to 130 of about 4,707,888 (270)

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Barriers and Enablers to Evaluating Outcomes From Public Involvement in Health Service Design: An Interpretive Description. [PDF]

Qual Health Res, 2023
Lloyd N, Hyett N, Kenny A.
europepmc   +1 more source

Design for Social and Environmental Enterprise [PDF]

, 2009
SEED Foundation undertakes action research to develop new, innovative ways for design to most effectively contribute towards sustainable development. The research that follows is not the result of academic investigations but rather, a culmination of 20 ...
Bowden, Flora, Brass, Clare
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

The Strategy of Touchpoints Agricultural Tourism Services Based on the Motivation of Tourists (Case Study: South Khorasan Saffron Farm)

گردشگری و اوقات فراغت
Agricultural endeavors alone are insufficient to meet the requirements of rural communities. Consequently, comprehensive investigations have been undertaken to assess the economic viability of tourism farms.
Seyed Ali FAREGH , Narges Rezaee
doaj  

Service architecture design for E-Businesses: A pattern-based approach [PDF]

, 2008
E-business involves the implementation of business processes over the Web. At a technical level, this imposes an application integration problem. In a wider sense, the integration of software and business levels across organisations becomes a significant
Gacitua-Decar, Veronica, Pahl, Claus
core  

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

A Telecommuting Experience Service Design Decision Model Based on BP Neural Network. [PDF]

Psychol Res Behav Manag, 2022
Wang W, Wei T, Yu S, Chen J, Yang X.
europepmc   +1 more source

Libraries in transition: evolving the information ecology of the Learning Commons: a sabbatical report [PDF]

, 2007
This sabbatical report studied various models in order to determine best practices for design, implementation and service of Leaning Commons, a library service model which functionally and spatially integrates library services, information technology ...
McMullen, Susan
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source