Results 191 to 200 of about 208,734 (256)

Mechanistic Insights Into How Acupuncture Modulates Host Immunity via the Gut Microbiota-Macrophage Axis. [PDF]

Immun Inflamm Dis
Yang T, Li M, Wu X.
europepmc   +1 more source

A Hepatocyte‐to‐Stellate Cell Axis Couples Alternate‐Day Fasting to Liver Fibrosis Resolution via ATG7 S‐Nitrosylation

Advanced Science, EarlyView.
Alternate‐day fasting suppresses mitochondrial complex II assembly via SDHAF4 to upregulate hepatocyte eNOS. The resulting nitric oxide S‐nitrosylates ATG7 at C184 in hepatic stellate cells, restraining autophagic flux and preventing their profibrotic activation.
Xueqiang Wang, Mengqi Zeng, Cunxiao Sun, Yuhan Gou, Zhaode Feng, Weiqiang Lv, Chaoying Yan, Hansen Wu, Pengfei Zhang, Jie Xu, Ke Cao, Hao Li, Mingge Ding, Zhongbo Liu, Xing Zhang, Jiankang Liu, Xuan Zou, Zhihui Feng   +17 more
wiley   +1 more source

Integrated Function-Based Intervention, Acceptance and Commitment Therapy, and ICT-Enabled Collaboration for Chronic Self-Injurious Behavior in an Adult with Severe Intellectual Disability: A Case Report. [PDF]

Yonago Acta Med
Inoue M, Yamanaka T, Okano T, Kadekaru R, Imakita T.   +4 more
europepmc   +1 more source

Compound Abrus cantoniensis Extract Alleviates AFB1‐Induced Liver Injury by Regulating PI3K‐AKT Pathway and Gut Microbiota/Butyrate Metabolism

Advanced Science, EarlyView.
ACCE has a good alleviating effect on AFB1‐induced liver injury, and this alleviating effect is related to the PI3K‐AKT pathway regulated by ACCE and the butyrate metabolism of gut microbiota. ABSTRACT Aflatoxin B1 (AFB1) is a potent hepatotoxin commonly ingested through contaminated food. Abrus cantoniensis Hance, a traditional Chinese medicinal herb,
Hongjie Hu, Ming cheng, Shiqi Zheng, Huixin Liu, Xiaofang Wei, Wenwen Yang, Hongchun Yang, Liuyang Yuan, Li Jiang, Jie Chen, Linglong Zhao, Yanchao Guo, Hongbin Si   +12 more
wiley   +1 more source

From Biological Models to Industrial Production: How Industry 4.0 Enables the Manufacturability and Scalability of Biomimetic Design. [PDF]

Biomimetics (Basel)
Koska A.
europepmc   +1 more source

Salvianolic Acid a Disrupts the HSP90α‐AKT‐PERK Ternary Complex to Alleviate Atherosclerosis by Activating Endoplasmic Reticulum Stress of Senescent Vascular Smooth Muscle Cells

Advanced Science, EarlyView.
Salvianolic acid A (SAA) selectively induces senescent vascular smooth muscle cell apoptosis, alleviating atherosclerosis. Mechanistically, SAA targets heat shock protein 90 alpha (HSP90α) to disrupt the protein inase B (AKT)‐PRKR‐Like Endoplasmic Reticulum Kinase (PERK) scaffold, driving ubiquitin‐proteasome‐dependent AKT degradation.
Xiuya Guan, Mengkai Lu, Xinhai Cui, Dawei Zhang, Lei Zhang, Lin Lin, Yuan Li, Yuanlong Hu, Chao Li   +8 more
wiley   +1 more source

Multi-objective location-routing optimization of first-mile pre-cooling distribution center networks in the agricultural cold chain. [PDF]

PLoS One
Ying C, Kim YJ.
europepmc   +1 more source

A Blockchain Platform for Vaccine Beneficiary Registration, Side Effects, Cold Supply Chain, and Personnel Training and Employment Management. [PDF]

Sensors (Basel)
Sadawi AA, Ndiaye MM, Al Khaffaf I, Abdulkarim O.   +3 more
europepmc   +1 more source

An Action-Centric Zero Trust Maturity Model for Agentic AI Environments. [PDF]

Sensors (Basel)
Mok JH, Jo H, Lee S.
europepmc   +1 more source

How to Implement a Ketogenic Diet Therapy in Developing Countries: Colombian Consensus on Ketogenic Diet Therapy Use in the Management of Adults with Drug-Resistant Epilepsy. [PDF]

Nutrients
Vergara-Aguilar JP, Lizcano A, Martinez-Perez A, Calle-López Y, Cervenka MC, Clavijo-Prado CA, Cotuá-Urzola JC, González W, González-Velásquez DK, Grillo-Ardila MCP, Martinez-Micolta P, Ramírez LM, Rincón-Franco N, Osorio JV, Villamil-Osorio LV, Tanner A.   +15 more
europepmc   +1 more source