A Micropeptide Component of the OGDH Complex Modulates ATP Production in the TCA Cycle
This study identified a mitochondrial micropeptide encoded by a non‐canonical open reading frame (alt‐ORF) within the CTSB gene. This micropeptide named APPM (ATP production‐promoting micropeptide) is a novel component of the OGDHc complex in the TCA cycle. APPM localizes to the inner mitochondrial membrane and directly binds to OGDH, the E1 subunit of
Xinqiang Yin +9 more
wiley +1 more source
Evaluating LLM Integration in Pharmacometrics Through a Software Development Perspective. [PDF]
Barrett K, Callisto SP.
europepmc +1 more source
China's Low‐Carbon Energy Transition Over the Past Two Decades: Experiences and Implications
China's low‐carbon energy transition features a brief decline and subsequent rebound in coal consumption, alongside the rapid expansion of renewable energy. This study develops a stage‐based analytical framework to explain this evolution from the perspectives of economic development, energy security, and environmental sustainability, revealing how ...
Yu Liu +3 more
wiley +1 more source
Promoting health through sports-medicine integration in China: a narrative and conceptual review of challenges, international. [PDF]
Yang Y, Jing G.
europepmc +1 more source
A Transformer‐based AI framework, DLINP, screens millions of compounds to identify Co68, a cobalt‐pincer organometallic complex that biases TLR4‐MD2 signaling toward antitumor interferon activation while suppressing inflammatory toxicity through an early TLR4‐SYK‐STAT1 axis.
Xuefei Guo +10 more
wiley +1 more source
OSI Stack Redesign for Quantum Networks: Requirements, Technologies, Challenges, and Future Directions. [PDF]
Ahmed S +6 more
europepmc +1 more source
Polymer‐based hydrogels have emerged as promising materials for atmospheric water harvesting (AWH) due to their high water affinity, tunable network structure, and excellent moisture adsorption‐desorption performance. Functional hydrogel systems enable efficient water capture and controlled release under low‐energy conditions, offering a sustainable ...
Swagata Datta +6 more
wiley +1 more source
Intelligent Congestion Control in the Internet of Vehicles Employing Network Slicing in 5G Architecture. [PDF]
Ahmad AW, Gul RS, Derawi M.
europepmc +1 more source
Additive Manufacturing of High‐Performance Polymers for Extreme Environments
Additive manufacturing of high‐performance polymers for extreme environments is critically reviewed through an integrated chemistry‐processing‐structure‐property‐qualification framework. The review compares fused filament fabrication, selective laser sintering, and direct ink writing, linking rheology and thermal history to crystallization, defect ...
Md Tofazzal Hossain +7 more
wiley +1 more source
Patient-Caregiver Dyads in Severe and Advanced COPD: Relationships, Caregiving Burden, and Intervention Support: A Narrative Review. [PDF]
Zu Y, Sun H, Luo D, Du Y.
europepmc +1 more source

