Results 41 to 50 of about 9,876,170 (146)

Methionine Regulates Antitumour Function of CD8+ T Cells Through Polyamine Synthesis

open access: yesImmunology, Volume 179, Issue 3, Page 418-433, November 2026.
Methionine restriction in vitro enhances CD8+ T cell effector function by suppressing polyamine synthesis and progressively induces the co‐expression of PD‐1 and TIM‐3. Consistently, sustained dietary methionine restriction diminishes the efficacy of adoptive T cell therapy (ACT) and promotes the expression of terminal exhaustion‐associated markers ...
Tian Zhao   +16 more
wiley   +1 more source

COMBO‐RATE: An Experimentally Validated Bioinformatic Tool to Identify Promiscuous HLA Restrictions

open access: yesHLA, Volume 108, Issue 5, November 2026.
ABSTRACT Defining HLA restriction of T cell epitopes is essential for understanding immune responses in infectious disease, autoimmunity and vaccine design. Current bioinformatic programmes, including the IEDB RATE tool, enable inference of single‐HLA restrictions from immune response data of HLA‐typed donors.
Jessica Nevarez‐Mejia   +8 more
wiley   +1 more source

VLAN-based Traffic Steering for Hierarchical Service Function Chaining

open access: yes, 2019
| openaire: EC/H2020/761898/EU//MATILDAAlong the increasing demands for complex networking services, big networking infrastructures, and network service providers aim to provide customized services to the users.
Hantouti, Hajar   +5 more
core   +1 more source

Translating Circularity Into Strategy: A Governance Meta‐Capability Framework

open access: yesBusiness Strategy and the Environment, Volume 35, Issue 6, Page 8746-8758, September 2026.
ABSTRACT Firms struggle to transition to circular economy (CE) models, often citing external barriers. Yet some firms succeed, whereas others fail: Why? We argue that success depends on a specific governance capability—a meta‐capability that allows firms to (1) sense and strategically reframe CE imperatives, (2) seize opportunities by aligning diverse ...
Felix Carl Schultz   +1 more
wiley   +1 more source

Architectural Strategies for Implementing and Automating Service Function Chaining (SFC) in Multi-Cloud Environments [PDF]

open access: yes, 2020
Service Function Chaining (SFC) represents a paradigm shift in the deployment, management, and automation of network services, enabling a dynamic approach to connecting virtual network functions (VNFs) in a prescribed sequence.
Velayutham, Arunkumar
core  

QoE-Aware Edge Computing Through Service Function Chaining

open access: yes, 2022
Mobile multimedia Internet services, such as mobile virtual reality (VR), request for advanced quality of experience (QoE) provision. In the future Internet, such a QoE provision will be leveraged through edge computing, which can be facilitated through ...
Foukalas F., Tziouvaras A.   +2 more
core   +1 more source

Distributed federated service chaining for heterogeneous network environments

open access: yes, 2021
Future networks are expected to support cross-domain, cost-aware and fine-grained services in an efficient and flexible manner. Service Function Chaining (SFC) has been introduced as a promising approach to deliver these services.
Lars Nagel (4482649)   +3 more
core   +3 more sources

LISP-Based Integrated Control Plane Framework for Service Function Chaining in Distributed Edge Clouds

open access: yesIEEE Access, 2021
Service function chaining, which provides a sequential set of multiple services in an end-to-end communication path, is a key technology for providing better service quality to users and efficient management of the network.
Kyoungjae Sun, Younghan Kim
doaj   +1 more source

From Thermodynamics to Dynamics: The Victoria Mode Reshapes Pacific Side of the Arctic Winter Sea Ice Growth

open access: yesEarth's Future, Volume 14, Issue 9, September 2026.
Abstract Despite widespread Arctic sea ice loss under global warming, early winter sea ice growth (SIG) in the Pacific side of the Arctic has displayed amplified interannual variability since 2007 —a phenomenon whose underlying mechanisms remain unclear.
Daling Li Yi   +4 more
wiley   +1 more source

A Reliability-Aware Approach for Resource Efficient Virtual Network Function Deployment

open access: yesIEEE Access, 2018
Network function virtualization (NFV) is a promising technique aimed at reducing capital expenditures (CAPEX) and operating expenditures (OPEX), and improving the flexibility and scalability of an entire network.
Jian Sun   +7 more
doaj   +1 more source

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