Results 91 to 100 of about 2,135,754 (281)

Aligning HIV treatment and hypertension clinic visits and dispensing as a first step towards service delivery integration in South Africa

open access: yesJournal of the International AIDS Society
Introduction Global and national guidelines recommend the integration of care for HIV and other chronic conditions to improve individual and public health outcomes.
Oratile Mokgethi   +6 more
doaj   +1 more source

Dynamic integration of context model constraints in web service processes [PDF]

open access: yes, 2009
Autonomic Web service composition has been a challenging topic for some years. The context in which composition takes places determines essential aspects. A context model can provide meaningful composition information for services process composition. An
Bandara, Kosala Yapa   +2 more
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

How did New Zealand's regional District Health Board groupings work to improve service integration and health outcomes: a realist evaluation. [PDF]

open access: yesBMJ Open, 2023
Penno E   +10 more
europepmc   +1 more source

An analysis of the possible causes of product market malfunctioning in the EU: First results for manufacturing and service sectors [PDF]

open access: yes
Within the context of the follow-up to the Single Market Review, the European Commission has screened EU manufacturing and service sectors for problems of market malfunctioning. This paper investigates the nature of these problems in the selected sectors
Adriaan Dierx   +2 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Parlay and OGSA based framework for service creation in NGN

open access: yesTongxin xuebao, 2007
A parlay and open grid services architecture(OGSA) based framework for service creation in NGN was pro-posed,which not only provided uniform access to heterogeneous network capabilities,but also built effective distributed convergence mechanisms beyond ...
LIU Zhen1   +3 more
doaj  

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

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