Results 71 to 80 of about 2,140,872 (281)

Experiences in Integrated Multi-Domain Service Management

, 1997
Increased competition, complex service provision chains and integrated service offerings require effective techniques for the rapid integration of telecommunications services and management systems over multiple organisational domains.
Bracht, Ralf, Lewis, David, McEwan, Alistair, Redmond, Cliff, Tiropanis, Thanassis, Wade, Vincent P.   +5 more
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Dynamic integration of context model constraints in web service processes [PDF]

, 2009
Autonomic Web service composition has been a challenging topic for some years. The context in which composition takes places determines essential aspects. A context model can provide meaningful composition information for services process composition. An
Bandara, Kosala Yapa, Pahl, Claus, Wang, MingXue   +2 more
core  

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

Molecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

Striving Towards an Active Local Information and Communication Strategy within the Context of the European Migration Policy

Social Work and Society, 2013
European migration law combines equal treatment within Europe and unequal treatment at the borders, while local migration policy aims at social inclusion, acceptance of diversity and equality.
Anja Van den Durpel
doaj  

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Service Integration: Supply Chain Integration in Servitization

, 2021
Research and empirical evidence indicates that servitization changes the traditional manufacturing supply chain. Firms engaged in servitization must integrate with a network of actors ranging from component suppliers to intermediaries to customers. To develop a comprehensive picture of supply chain integration in the servitization context, this chapter
openaire   +3 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Collaboration between information exchange between physiotherapists in primary and specialist health services – a systematic coproduction

Fysioterapeuten
Purpose: It appears to be inadequate communication and a lack of information transfer between physiotherapists in the specialist (SH) and primary health services (PH).
Ingeborg Marie Hegland Thorsen, Berit Hagemoen Linberg, Anne Marit Mengshoel   +2 more
doaj  

Inter-Domain Integration of Services and Service Management

, 1997
The evolution of the global telecommunications industry into an open services market presents developers of telecommunication service and management systems with many new challenges.
Bracht, Ralf, Lewis, David, McEwan, Alistair, Redmond, Cliff, Tiropanis, Thanassis, Wade, Vincent   +5 more
core