Myogenic Fusogen‐Engineered Lipid Nanoparticles Enhance mRNA Delivery in Skeletal Muscle
This study reports a biomimetic strategy of engineering full‐length Myomaker, a muscle‐specific fusogen, into lipid nanoparticles (LNPs) to harness the native myoblast fusion capability for skeletal muscle mRNA delivery. The resulting Mymk‐LNPs enhance transfection in differentiating myocytes and enable Cre‐mediated reporter activation in injured ...
Fangyu Zhang +18 more
wiley +1 more source
Consumer-expressed needs concerning age-friendly products in China: a computational grounded theory analysis of online reviews. [PDF]
Li Z, Fu Z, Zhu Q, He K.
europepmc +1 more source
Here, we develop a high‐throughput algorithm that accelerates the elucidation of phase diagrams of topological spin textures using limited computational resources at high numerical accuracy. Applying this framework to the van der Waals magnet CrSBr, we unveiled a hierarchy of previously unknown topological textures (domain‐wall bimerons, bimeron chains,
Andrew Lyall +4 more
wiley +1 more source
Resilience enhancement-oriented traffic police service district division and patrol route planning. [PDF]
Ju Y +6 more
europepmc +1 more source
A removable sacrificial polymer layer engineers the thermal boundary condition during nanosecond laser ablation of PET, suppressing heat‐affected‐zone formation without relying on costly ultrafast lasers. This strategy enables deep, high‐aspect‐ratio trenches with no detectable heat‐affected zone, templating silver‐filled mesh electrodes with record ...
Mehdi Zarei +3 more
wiley +1 more source
Analysis of the efficiency and sustainability of the underground loop in Hangzhou Future Science and Technology City. [PDF]
Zhang H, Yu Q.
europepmc +1 more source
Borophene is introduced as a programmable 2D bio‐interface that organizes DNA through dual boron–sulfur and nucleobase interactions. This molecular architecture enables efficient long‐range nanosurface energy transfer, establishing new design principles for functional nano–bio interfaces and amplification‐free optical biosensing.
Teresa Aditya +11 more
wiley +1 more source
Circular-economy residual-value assessment of retired lithium-ion batteries via degradation prediction and game-theoretic subsidies. [PDF]
Lan G, Chen Y, Yao D, Wang J.
europepmc +1 more source
Biodegradable 3D‐Printable and Coatable Antifouling Composites for Marine Applications
Marine biofouling damages submerged surfaces and raises greenhouse gas emissions. Biodegradable antifouling biocomposites were developed by hot‐mixing beeswax, Tween 80, and calcium stearate or stearic acid. Adjusting the component ratio enables processing via hot‐pressing, 3D‐printing, or dip‐coating.
Gabriele Corigliano +17 more
wiley +1 more source
Service-Based RAN User Plane Decoupling and Orchestration via ComBERT for AI AgentServices. [PDF]
Ding H +7 more
europepmc +1 more source

