Results 51 to 60 of about 13,113,594 (311)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
HSE's Performance Assurance Report - Management Data Report March 2018 [PDF]
, 2018 HSE's Performance Assurance Report (PAR) provides an overall analysis of key performance data from Divisions, such as Acute, Mental Health, Social Care, Primary Care, Health and Wellbeing as well as Finance and HR.
Health Service Executive (HSE)
core
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Design dimensions of experience rooms for service test drives : case studies in several service contexts [PDF]
, 2010 Purpose - The objective of this exploratory study is to analyse "test drives" of service offerings in a variety of service contexts by applying existing design dimensions of experience rooms in order to develop some principles to assist service designers
Edvardsson, Bo +8 more
core +1 more source
International Journal of Strength and ConditioningThe purpose of this investigation was to establish the reliability and concurrent validity of measures of peak and early force production obtained from a portable isometric dynamometer (PID).
Danny Lum +3 more
doaj +1 more source
Performance of network and service monitoring frameworks [PDF]
2009 IFIP/IEEE International Symposium on Integrated Network Management, 2009 The efficiency and the performance of anagement systems is becoming a hot research topic within the networks and services management community. This concern is due to the new challenges of large scale managed systems, where the management plane is integrated within the functional plane and where management activities have to carry accurate and up-to ...
Lahmadi, Abdelkader +2 more
openaire +3 more sources
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
BMC Medical EducationBackground Laparoscopic surgery places musculoskeletal demands on surgeons, which may be exacerbated by daily clinical activity. The effect of a workday on simulated laparoscopic performance and musculoskeletal parameters remains poorly understood ...
Vincent Dochez +5 more
doaj +1 more source
Fatigue life analysis of main landing gear structure considering shock absorber travel
Hangkong gongcheng jinzhanThe fatigue life assessment for landing gears is challenging due to complexity of load cases and variation of shock absorber travel （SAT）. Focusing on the high-cycle fatigue （HCF） issue of the piston sliding tube （PSL），based on the whole geometric model ...
LIU Panglun +6 more
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source