Results 111 to 120 of about 235,237 (311)

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Caring in the Context of Systems: Service Provider Perspectives on the Mental Health Needs of Newcomer Young Men. [PDF]

Community Health Equity Res Policy, 2023
Tulli-Shah M, Hilario C, Salami B, Pui-Hing Wong J.   +3 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Community service providers' roles in supporting communication disability rehabilitation in Majority World contexts: An example from Ghana

, 2019
Karen Wylie, Bronwyn Davidson, Julie Marshall, Josephine Ohenewa Bampoe, Clement Amponsah, Lindy McAllister   +5 more
openalex   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Providing educational services

Community Eye Health Journal, 2007
At least eighty per cent of the world's visually impaired children live in low- and middle-income countries, where less than ten per cent of them have access to education. This sad fact almost guarantees that these children face a lifetime of poverty and illiteracy.
Campbell Larry, MNG Mani
openaire   +1 more source

Arrangements for the Transfer of Social-Services Delivery to Non-Governmental Providers (Regional Practices, Russia) [PDF]

, 2019
Galina M. Zabolotnaya, Andrey Larionov
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

48, XXXX, A Rare Aneuploidy

Balkan Journal of Medical Genetics, 2009
Kaur A, Pandhi M, Singh J
doaj   +1 more source

IT Audit of IT Service Provider Using COBIT 4.1 Framework: Case Study at PT. XYZ [PDF]

, 2017
Muhammad Malik Hakim
openalex   +1 more source