Results 121 to 130 of about 981,793 (347)
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu+6 more
wiley +1 more source
UPDATE: Consistency of Home Care Personnel Under Managed Competition: A Case Study from Ontario (Shortened Version Presented at the Knowledge to Wisdom Conference) [PDF]
Measuring Consistency of Personnel in Home care: Current Challenges and Findings Consistency of personnel is important to ensuring continuity of care for home care clients.
Brian Hutchison+3 more
core
Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui+3 more
wiley +1 more source
Understanding Health Plan Types: What\u27s in a Name? [PDF]
Every year, many employers conduct an open season to let employees select or change their medical plans. Several factors may affect their selection, including choice of care provider and shared cost.
Briscoe, Bonita
core +1 more source
Signposting services for people with health and care needs: a rapid realist review
Background Signposting typically refers to an informal process that involves giving information to patients to enable them to access external services and support. It is perceived to reduce demand on primary care and other urgent care services.
Anna Cantrell+2 more
doaj +1 more source
Tryptophan metabolite atlas uncovers organ, age, and sex‐specific variations
Tryptophan metabolites were analyzed across twelve organs, the central nervous system, and serum in male and female mice at three life stages. We found tissue‐, sex‐, and age‐specific differences, including increased indole‐3‐pyruvate and kynurenine in aging males.
Lizbeth Perez‐Castro+8 more
wiley +1 more source
Working Report #2: Client and Community Relations (Service Provider Perspectives) [PDF]
This report addresses two important questions: how much emphasis is placed on building positive relationships with families and communities across agency based, integrated service, and community and school based models of service delivery?
Cameron, Gary, Hazineh, Lirondel
core +1 more source
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel+9 more
wiley +1 more source
The Tromsø study: factors affecting patient‐initiated and provider‐initiated use of health care services [PDF]
Knut Fýlkesnes+2 more
openalex +1 more source
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan+6 more
wiley +1 more source