Results 231 to 240 of about 5,034,219 (303)

Reversible, Chemically Gated FRET via Ligand‐Activated Acceptors

Advanced Science, EarlyView.
Fluorogen binding turns the compact FAST tag into a tunable FRET acceptor, with ligand chemistry programming spectral overlap and excited‐state lifetimes. Fluorescence‐lifetime imaging reads out energy transfer through the shortened donor lifetime, while simply adding or washing out the dye switches FRET on and off, reversibly mapping the supramodular ...
Nivedita Singh, Smruti Ranjan Nayak, Sanjay Kumar Mohanty, Aishwarya Hanumantharaju, Amala Shaju, Mini Jose, Aravind Penmatsa, Deepak Nair   +7 more
wiley   +1 more source

Bringing treatment home for adolescents with eating disorders. [PDF]

BJPsych Open
Coglan L, Combe G, McGuigan L, Ayton A.
europepmc   +1 more source

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

Advanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen, Zhiquan Liu, Wenmin Wang, Qing Wang, Tia J. Kowal, Fan Zhang, Grzegorz Walkiewicz, Faruk Hossen, Herbert M. Lachman, Jinqiong Zhou, Yiting Wang, Yang Sun   +11 more
wiley   +1 more source

Designing hospitality for health: an emerging approach to public health. [PDF]

Front Public Health
Howell BD, Steffy L, Hill JR, Parks R, Silva I, Ramly E, Holden RJ.   +6 more
europepmc   +1 more source

TP53 Loss Elevates NF‐κB‐IFN‐β‐MHC‐Ia Signaling to Promote NK Cell Resistance in Osteosarcoma

Advanced Science, EarlyView.
TP53 loss in a transforming or osteosarcoma cell promotes cytosolic DNA accumulation, activating NF‐κB‐dependent IFN‐β production. Autocrine IFN‐β signaling increases cell‐surface HLA‐Ia expression, strengthens inhibitory KIR signaling in natural killer cells, and thereby enables the affected cell to evade NK cell‐mediated cytotoxicity.
Guihui Qin, Cheung Kwan Yeung, Ye Yi, Dejin Zheng, Miaoman Ye, Chi‐Chong Chio, Jinjie Wu, Siyi Fu, Chu‐Xia Deng, Ren‐He Xu   +9 more
wiley   +1 more source

Over Half of Patients Progress to Cartilage Restoration After Initial Cartilage Biopsy in a Military Population. [PDF]

Arthrosc Sports Med Rehabil
Sanborn RM, Pluta NA, Fellows KJ, Cruz CA, Patzkowski JC, Cognetti DJ.   +5 more
europepmc   +1 more source

Clinical Color Match and Marginal Discoloration of a Universal Shade Composite Versus a Multi-shade Nanohybrid Composite in Anterior Teeth. [PDF]

Cureus
Fulzele E, Jaju N, Rathaur S, Gupta PK, Singh A, Ojha S.   +5 more
europepmc   +1 more source

Seaweed carbon removal cannot keep up with climate-driven loss. [PDF]

PLoS Biol
Filbee-Dexter K, Pessarrodona A, Krumhansl KA, Wernberg T.   +3 more
europepmc   +1 more source

Experimental Validation of a Distributed 5G Core with Store-and-Forward for IoT Sensing over LEO Non-Terrestrial Networks. [PDF]

Sensors (Basel)
Baeza VM, Romero Soto FX, Parada R, Monzo C.   +3 more
europepmc   +1 more source