Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Service User Experiences and Perspectives of Social Prescribing Services for Mental Health. [PDF]
Cooper M +4 more
europepmc +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Trauma-Informed Care on mental health wards: staff and service user perspectives. [PDF]
Nikopaschos F +5 more
europepmc +1 more source
From the chemical imbalance to the power imbalance: A psychiatry trainee's perspectives on service-user supervision. [PDF]
Bhagavan C, Gordon S, Sundram F.
europepmc +1 more source
Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay +2 more
wiley +1 more source
Staff and service user perspectives of a co-located homelessness centre in Scotland: a mixed-methods evaluation. [PDF]
Ng L, Donaghy E, Conway J, Mercer SW.
europepmc +1 more source
Pathways and pitfalls: a qualitative study of student experiences in biomedical science education
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell +8 more
wiley +1 more source
Exploring pathways to compulsory detention in psychiatric hospital and ways to prevent repeat detentions; Service user perspectives. [PDF]
Birken M +17 more
europepmc +2 more sources
Navigating Mental Health Services as an (Im)Perfect Service User. [PDF]
Jackson S.
europepmc +1 more source

