Results 91 to 100 of about 563,218 (303)

Commentary on" Evaluating service users’ experiences of using Talking Mats®" [PDF]

open access: yes, 2018
Purpose: This paper provides some thoughts following on from reading: Evaluating service users’ experiences of using Talking Mats®. Design/methodology/approach: This commentary outlines some considerations for the continued discussions about how to ...
Harding, C., Stewart, A.
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

User involvement in service innovations

open access: yes, 2022
The importance of user orientation in innovation activities is nowadays emphasized not only in business life but also in political and societal discussions. In today's competed and changing market situations, one promising way to support market success are innovations originating from the needs of the customers.
Kaasinen, Eija   +6 more
openaire   +2 more sources

Participatory Research Into Inclusive Practice: Improving Services for People With Long Term Neurological Conditions

open access: yesForum: Qualitative Social Research, 2017
People with long-term conditions are intensive users of health services as well as being long term users of social care and community services. In the UK, the Department of Health has suggested that the development of a more inclusive approach to ...
Tina Cook, Helen Atkin, Jane Wilcockson
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

The Maudsley Biomedical Research Centre (BRC) data linkage service user and carer advisory group: creating and sustaining a successful patient and public involvement group to guide research in a complex area

open access: yesResearch Involvement and Engagement, 2019
Background Patient and Public Involvement (PPI) in health and social care research has been shown to improve the quality and relevance of research.
Amelia Jewell   +9 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Democratic Learning for Democratic Practice: Co-Operation and Deliberation [PDF]

open access: yes, 2015
In this chapter we suggest that education for a critical understanding of democracy is central to the delivery of high-quality patient-centred care. Development of skills and knowledge which support change in practice can and must be brought into the ...
Carey, Linda   +3 more
core  

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